Medhat Farwati, Tolga Aksu, Enrique I Pachon, Tomas Santillana, Carlos Thiene Pachon, Pasquale Santangeli, Jose Carlos Pachon
{"title":"Cardioneuroablation: Three different approaches.","authors":"Medhat Farwati, Tolga Aksu, Enrique I Pachon, Tomas Santillana, Carlos Thiene Pachon, Pasquale Santangeli, Jose Carlos Pachon","doi":"10.1016/j.pcad.2025.04.003","DOIUrl":null,"url":null,"abstract":"<p><p>Cardioneuroablation (CNA) is an emerging therapy for patients with vasovagal syncope with predominant cardioinhibitory responses. The procedure targets the neuromyocardial connections localized in specific regions of the right and left atrium as well as the adjacent ganglionated plexi (GP) providing parasympathetic innervation to the sinus and atrioventricular nodes. The target regions for CNA can be determined with various techniques, which result in heterogenous procedural approaches and endpoints in different centers specialized in this procedure. In this review we summarize the rationale and details of the procedural approach for three different techniques for CNA, namely: CNA controlled by extra-cardiac vagal stimulation, CNA guided by analysis of fractionated electrograms, and an anatomical approach to CNA.</p>","PeriodicalId":94178,"journal":{"name":"Progress in cardiovascular diseases","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Progress in cardiovascular diseases","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1016/j.pcad.2025.04.003","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Cardioneuroablation (CNA) is an emerging therapy for patients with vasovagal syncope with predominant cardioinhibitory responses. The procedure targets the neuromyocardial connections localized in specific regions of the right and left atrium as well as the adjacent ganglionated plexi (GP) providing parasympathetic innervation to the sinus and atrioventricular nodes. The target regions for CNA can be determined with various techniques, which result in heterogenous procedural approaches and endpoints in different centers specialized in this procedure. In this review we summarize the rationale and details of the procedural approach for three different techniques for CNA, namely: CNA controlled by extra-cardiac vagal stimulation, CNA guided by analysis of fractionated electrograms, and an anatomical approach to CNA.
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