[A Case of Recurrent Tracheal Adenoid Cystic Carcinoma Treated with Multidisciplinary Therapy].

Abstract

Tracheal adenoid cystic carcinoma(TACC)is relatively rare. Therapy for recurrent TACC has not yet been established. A woman in her late 80s was diagnosed with TACC just below the vocal folds. At the same time, a solitary lung metastasis in the right upper lobe was detected on admission. After tracheal tumor resection using rigid bronchoscopy, radiation therapy 40 Gy was administered. Subsequently, right upper lobectomy was performed. Two years after first admission(FA), radiation therapy 35 Gy for tracheal recurrence was performed. Two years and 6 months after FA, wedge resection was performed for metastases to the left lung. Three years after FA, multiple bilateral lung metastases were detected, and pembrolizumab was administered. Four years after FA, bloody sputum due to local tracheal recurrence was observed, and photodynamic therapy was initiated. Six years after FA, tracheostomy and tracheal cauterization under rigid bronchoscopy were performed for airway stenosis. At that time(7 years after FA), the patient was undergoing second-line chemotherapy. We report a case of recurrent TACC treated with multidisciplinary therapy.