[Partial Nephrectomy and Focal Therapy in Small Renal Tumors].

Q4 Medicine
Yoshiyuki Matsui
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引用次数: 0

Abstract

With the increasing use of robot-assisted surgery, partial nephrectomy is recommended for small renal tumors(T1a)with a tumor size of 4 cm or less and is now considered a standard treatment. However, with the rise in incidental detection of small renal tumors during routine screenings, especially in elderly patients or those with comorbidities who may hesitate to undergo general anesthesia, there is a growing need for alternative treatments such as focal therapy to partial nephrectomy. The main methods of focal therapy include ablation techniques such as cryotherapy and radiofrequency ablation. Recently, stereotactic body radiotherapy has also been approved for insurance coverage, emerging as a minimally invasive option for renal cell carcinoma with a tumor size of 5 cm or less. Additionally, although not a focal therapy, active surveillance is also considered an effective option for very small renal tumors. Among these various treatment options, shared decision making between patients and healthcare providers, considering factors such as tumor characteristics and patient-specific conditions, is considered crucial in determining the appropriate treatment strategy for small renal tumors. In the absence of large-scale prospective comparative trials on partial nephrectomy, ablation therapy, stereotactic radiotherapy, and active surveillance, this paper provides an overview of the characteristics of each treatment modality and their respective outcomes and discusses the future perspectives in the treatment of small renal tumors.

[小肾肿瘤的肾部分切除术和病灶治疗]。
随着机器人辅助手术的使用越来越多,部分肾切除术被推荐用于肿瘤大小为4厘米或更小的小肾肿瘤(T1a),现在被认为是一种标准治疗方法。然而,随着常规筛查中偶然发现的小肾肿瘤的增加,特别是在老年患者或有合并症的患者中,他们可能不愿接受全身麻醉,因此越来越需要替代治疗,如局部治疗而不是部分肾切除术。病灶治疗的主要方法包括消融技术,如冷冻治疗和射频消融。最近,立体定向放射治疗也被批准纳入保险范围,作为肿瘤大小为5cm或更小的肾细胞癌的一种微创选择。此外,虽然不是局灶性治疗,主动监测也被认为是非常小的肾肿瘤的有效选择。在这些不同的治疗方案中,考虑到肿瘤特征和患者特定条件等因素,患者和医疗保健提供者之间的共同决策被认为是确定小肾肿瘤适当治疗策略的关键。在缺乏关于肾部分切除术、消融治疗、立体定向放疗和主动监测的大规模前瞻性比较试验的情况下,本文概述了每种治疗方式的特点及其各自的结果,并讨论了小肾肿瘤治疗的未来前景。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
0.20
自引率
0.00%
发文量
337
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