[A Case of Long-Term Prognosis of Advanced Rectosigmoid Cancer with Multiple Metastases Treated with Multidisciplinary Therapy].

Abstract

The case was 50-year-old woman, who was diagnosed with advanced rectosigmoid cancer with multiple liver metastases and solitary lung metastasis. She was started with chemotherapy. Two courses of mFOLFOX6+panitumumab and 8 courses of mFOLFOX6+bevacizumab were administered as a first-line. As a second-line, 1 course of FOLFIRI+ramucirumab was given. Six months later, CT showed that lung metastasis had disappeared and all liver metastases had become smaller, therefor surgery was selected. Laparoscopic partial hepatectomy was performed, and 2 months later, laparoscopic high anterior resection was added. She received 4 courses of capecitabine as adjuvant chemotherapy, but the lung metastasis had enlarged, and thoracoscopic partial lung resection was performed. Five months later, a nodule suspected metastasis was noted on the dissected surface of liver S5 on CT, and a right liver lobectomy was added. She was surviving for 2 years and 10 months after diagnosis of Stage Ⅳ rectal cancer, and had been progression-free for 10 months after last treatment.