Effects of pneumocephalus on electrode location after deep brain stimulation of the subthalamic nucleus in Parkinson's disease.

IF 1.9 4区医学 Q3 CLINICAL NEUROLOGY

World neurosurgery Pub Date : 2025-04-04 DOI:10.1016/j.wneu.2025.123958

Yi Wang, Hongliang Mao, Xiaoming Kong, Liangchen Yu, Jianyu Nie, Yue Liu, Hongwei Cheng

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引用次数: 0

Abstract

Objective: This study investigates the impact of pneumocephalus on electrode positioning following subthalamic nucleus deep brain stimulation (STN-DBS) in patients with Parkinson's disease (PD).

Methods: A retrospective analysis was performed on 111 patients who underwent bilateral STN-DBS at the First Affiliated Hospital of Anhui Medical University. Preoperative MRI and postoperative CT scans were utilized to assess electrode positions and pneumocephalus volume. The brain imaging data were standardized to the Montreal Neurological Institute (MNI) space for precise comparison. Statistical analyses were performed to identify factors influencing the volume of pneumocephalus.

Results: This study found that pneumocephalus absorption significantly affects electrode positioning, leading to a forward and upward shift. A higher degree of brain atrophy and a higher number of microelectrode recording (MER) passages were significantly correlated with increased pneumocephalus volume and more pronounced electrode displacement.

Conclusion: Pneumocephalus plays a critical role in electrode displacement during STN-DBS surgery. Minimizing cerebrospinal fluid (CSF) loss and careful planning of MER passages are essential for improving surgical accuracy. Further studies with larger sample sizes and multicenter data are needed to validate these findings and increase their generalizability.

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脑积水对帕金森病患者丘脑下核深部脑刺激后电极定位的影响。

目的：探讨脑积水对帕金森病（PD）患者丘脑下核深部脑刺激（STN-DBS）后电极定位的影响。方法：对在安徽医科大学第一附属医院行双侧STN-DBS的111例患者进行回顾性分析。术前MRI和术后CT扫描用于评估电极位置和气头体积。脑成像数据被标准化到蒙特利尔神经学研究所（MNI）空间进行精确比较。统计分析确定影响尘肺体积的因素。结果：本研究发现，脑气吸收明显影响电极定位，导致电极向前和向上移动。较高程度的脑萎缩和较高数量的微电极记录（MER）通道与脑气体积增加和更明显的电极位移显著相关。结论：脑积水在STN-DBS手术中电极移位起关键作用。减少脑脊液（CSF）损失和仔细规划MER通道对于提高手术准确性至关重要。需要更大样本量和多中心数据的进一步研究来验证这些发现并增加其普遍性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

World neurosurgery CLINICAL NEUROLOGY-SURGERY

CiteScore

3.90

自引率

15.00%

发文量

1765

审稿时长

47 days

期刊介绍： World Neurosurgery has an open access mirror journal World Neurosurgery: X, sharing the same aims and scope, editorial team, submission system and rigorous peer review. The journal''s mission is to: -To provide a first-class international forum and a 2-way conduit for dialogue that is relevant to neurosurgeons and providers who care for neurosurgery patients. The categories of the exchanged information include clinical and basic science, as well as global information that provide social, political, educational, economic, cultural or societal insights and knowledge that are of significance and relevance to worldwide neurosurgery patient care. -To act as a primary intellectual catalyst for the stimulation of creativity, the creation of new knowledge, and the enhancement of quality neurosurgical care worldwide. -To provide a forum for communication that enriches the lives of all neurosurgeons and their colleagues; and, in so doing, enriches the lives of their patients. Topics to be addressed in World Neurosurgery include: EDUCATION, ECONOMICS, RESEARCH, POLITICS, HISTORY, CULTURE, CLINICAL SCIENCE, LABORATORY SCIENCE, TECHNOLOGY, OPERATIVE TECHNIQUES, CLINICAL IMAGES, VIDEOS