Recent Research Progress of Wound Healing Biomaterials Containing Platelet-Rich Plasma.

IF 6.6 2区医学 Q1 NANOSCIENCE & NANOTECHNOLOGY

International Journal of Nanomedicine Pub Date : 2025-03-31 eCollection Date: 2025-01-01 DOI:10.2147/IJN.S506677

Sha Huang, Qing Li, Xiangyu Li, Hailing Ye, Luyang Zhang, Xiaoyi Zhu

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引用次数: 0

Abstract

Platelet-Rich Plasma (PRP) is a plasma product obtained by centrifuging autologous blood, containing a high concentration of platelets, white blood cells, and fibrin. PRP is enriched with various growth factors, such as Transforming Growth Factor-beta (TGF-β), Platelet-Derived Growth Factor (PDGF), Epidermal Growth Factor (EGF), Insulin-Like Growth Factor (IGF), and Vascular Endothelial Growth Factor (VEGF), all of which promote tissue growth and repair. Currently, PRP has been widely applied in the clinical field of wound repair and has achieved certain therapeutic effects. Biomaterials, as an important direction in the treatment of wounds, combined with PRP, provide new possibilities to enhance the regenerative repair of wounds by PRP. This article reviews the latest research progress of biomaterials combined with PRP in the treatment of wounds, aiming to provide references for PRP wound treatment, as well as to provide ideas for the development of subsequent medical materials.

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富血小板血浆伤口愈合生物材料的研究进展。

富血小板血浆（PRP）是通过离心获得的血浆产品，含有高浓度的血小板、白细胞和纤维蛋白。PRP富含多种生长因子，如转化生长因子-β (TGF-β)、血小板源性生长因子（PDGF）、表皮生长因子（EGF）、胰岛素样生长因子（IGF）、血管内皮生长因子（VEGF）等，促进组织生长和修复。目前，PRP已广泛应用于伤口修复的临床领域，并取得了一定的治疗效果。生物材料作为创伤治疗的一个重要方向，与PRP相结合，为PRP增强伤口再生修复提供了新的可能性。本文综述了生物材料与PRP在伤口治疗中的最新研究进展，旨在为PRP伤口治疗提供参考，并为后续医用材料的开发提供思路。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

International Journal of Nanomedicine NANOSCIENCE & NANOTECHNOLOGY-PHARMACOLOGY & PHARMACY

CiteScore

14.40

自引率

3.80%

发文量

511

审稿时长

1.4 months

期刊介绍： The International Journal of Nanomedicine is a globally recognized journal that focuses on the applications of nanotechnology in the biomedical field. It is a peer-reviewed and open-access publication that covers diverse aspects of this rapidly evolving research area. With its strong emphasis on the clinical potential of nanoparticles in disease diagnostics, prevention, and treatment, the journal aims to showcase cutting-edge research and development in the field. Starting from now, the International Journal of Nanomedicine will not accept meta-analyses for publication.