Sclerosing liposarcoma with rib involvement detected by CT and 99mTc-MDP bone scintigraphy: A case report and review of the literature.

Abstract

A 70-year-old male patient who presented with persistent upper abdominal pain was found to have a rare case of sclerosing liposarcoma with rib involvement. Despite the absence of significant weight loss or a history of infectious disease, elevated inflammatory markers suggested an underlying inflammatory or neoplastic process. Diagnostic imaging by computed tomography (CT) and single photon emission computed tomography (SPECT) played a critical role in identifying a soft tissue mass causing osteolytic damage to the left 9^th rib. The rapid enlargement of the lesion and the specific imaging characteristics challenged conventional detection methods. Biopsy confirmed the diagnosis of low-grade sclerosing liposarcoma. This case highlights the range of abilities of current imaging modalities in detecting certain forms of liposarcoma and emphasizes the need for a comprehensive diagnostic approach that integrates clinical findings, radiology, and pathology to accurately diagnose and manage such complex cases.