Severe Hemolytic Crisis in Uncontrolled AIHA Triggered by Dengue.

IF 0.8 Q3 MEDICINE, GENERAL & INTERNAL
Case Reports in Medicine Pub Date : 2025-03-29 eCollection Date: 2025-01-01 DOI:10.1155/carm/8165658
Christian Alberto Rodriguez-Saldaña, Sofía Cavalcanti-Ramírez, Carmen Claudia Quesada-Osoria, Luis Gabriel Farfan-Chavez, Guiovanna María Wong-Terrones, Helena Karin Dominguez-Troncos
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引用次数: 0

Abstract

We present the case of a woman with a history of autoimmune hemolytic anemia (AIHA), untreated for 1 year, who presented with fever, myalgia, arthralgia, anemia, and thrombocytopenia, along with a positive nonstructural protein antigen 1 (NS1Ag) test. During the course of dengue, the patient developed severe hemolytic anemia, posing a potentially life-threatening scenario due to the rapid decline in hemoglobin levels and the risk of multiorgan failure. Treatment with methylprednisolone was initiated alongside supportive care for dengue, and balancing corticosteroid risks in a viral infection was crucial to stabilize the patient, ultimately leading to a favorable outcome. This case highlights the importance of prompt diagnosis and integrated management of autoimmune diseases and viral coinfections in dengue-endemic areas.

登革热引发未控制AIHA的严重溶血性危象。
我们报告一名有自身免疫性溶血性贫血(AIHA)病史的女性,未经治疗1年,表现为发热、肌痛、关节痛、贫血和血小板减少,并伴有非结构蛋白抗原1 (NS1Ag)检测阳性。在登革热过程中,患者出现严重的溶血性贫血,由于血红蛋白水平迅速下降和多器官衰竭的风险,可能危及生命。甲基强的松龙治疗与登革热的支持性治疗同时开始,在病毒感染中平衡皮质类固醇风险对于稳定患者至关重要,最终导致有利的结果。该病例突出了在登革热流行地区及时诊断和综合管理自身免疫性疾病和病毒合并感染的重要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Case Reports in Medicine
Case Reports in Medicine MEDICINE, GENERAL & INTERNAL-
CiteScore
1.70
自引率
0.00%
发文量
53
审稿时长
13 weeks
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