Sacred codes: Preservation, permutation and expression

IF 4.1 3区医学 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY

Biomedical Journal Pub Date : 2025-04-01 DOI:10.1016/j.bj.2025.100852

Aila Akosua Kattner

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引用次数: 0

Abstract

This issue of the Biomedical Journal features a special section on epigenetics in infection, exploring epitranscriptomic modifications in the malaria parasite Plasmodium and the African sleeping sickness parasite Trypanosoma, with a focus on how these modifications influence parasite development and survival strategies. Additionally, this issue reviews regulatory mechanisms in asymmetric cell division, assessment needs for children with developmental coordination disorder along with recommendations, and advancements in 3D chondrocyte culturing for tissue engineering. Also examined are three key pathways exacerbating long COVID, the increasing impact of electromagnetic exposure in built environments on human health, and recent updates in liver transplantation criteria for hepatocellular carcinoma complicated by portal vein tumor thrombosis. Research in bladder cancer investigates the role of activating transcription factor 3, known for its anti-tumor properties, and its link to metformin. Another study demonstrates the efficacy of Sanger sequencing in streamlining mitochondrial disorder diagnostics, enabling timely identification based on clinical evidence. Additional studies present a novel intervention approach for autoimmune diseases, advancements in artificial bone grafts to enhance bone regeneration, and the benefits of public hospital participation in oncological clinical trials. Finally, a study confirms the suitability of transthoracic echocardiography for diagnosing suspected acute aortic syndrome.

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神圣代码：保存、排列和表达。

本期《生物医学杂志》的特色栏目是 "感染中的表观遗传学"，探讨了疟原虫和非洲昏睡病寄生虫锥虫的表观转录组修饰，重点关注这些修饰如何影响寄生虫的发育和生存策略。此外，本期还回顾了不对称细胞分裂的调控机制、发育协调障碍儿童的评估需求及建议，以及用于组织工程的三维软骨细胞培养的进展。此外，本期还探讨了导致长COVID恶化的三个关键途径、建筑环境中的电磁暴露对人类健康日益增加的影响，以及肝细胞癌并发门静脉肿瘤血栓形成的肝移植标准的最新进展。对膀胱癌的研究调查了以抗肿瘤特性著称的活化转录因子 3 的作用及其与二甲双胍的联系。另一项研究展示了桑格测序在简化线粒体疾病诊断方面的功效，从而能够根据临床证据及时进行鉴定。其他研究介绍了一种治疗自身免疫性疾病的新型干预方法、人工骨移植在促进骨再生方面的进展，以及公立医院参与肿瘤临床试验的益处。最后，一项研究证实经胸超声心动图适用于诊断疑似急性主动脉综合征。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Biomedical Journal Medicine-General Medicine

CiteScore

11.60

自引率

1.80%

发文量

128

审稿时长

42 days

期刊介绍： Biomedical Journal publishes 6 peer-reviewed issues per year in all fields of clinical and biomedical sciences for an internationally diverse authorship. Unlike most open access journals, which are free to readers but not authors, Biomedical Journal does not charge for subscription, submission, processing or publication of manuscripts, nor for color reproduction of photographs. Clinical studies, accounts of clinical trials, biomarker studies, and characterization of human pathogens are within the scope of the journal, as well as basic studies in model species such as Escherichia coli, Caenorhabditis elegans, Drosophila melanogaster, and Mus musculus revealing the function of molecules, cells, and tissues relevant for human health. However, articles on other species can be published if they contribute to our understanding of basic mechanisms of biology. A highly-cited international editorial board assures timely publication of manuscripts. Reviews on recent progress in biomedical sciences are commissioned by the editors.