Surgery or Non-invasive Treatment for Superficial Basal Cell Carcinoma: Does a Patient Decision Aid Help to Make a Personalized Treatment Decision?

IF 3.5 4区 医学 Q1 DERMATOLOGY
Lieke C J Van Delft, Myrthe M G Moermans, Brigitte A B Essers, Patty J Nelemans, Klara Mosterd, Marieke E C Van Winden, Satish F K Lubeek, Nicole W J Kelleners-Smeets
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Abstract

Patients with a superficial basal cell carcinoma can be treated surgically or non-invasively, all with specific (dis)advantages. An investigation was undertaken into whether the preference for surgery or non-invasive treatment of a superficial basal cell carcinoma differs between patients who used a patient decision aid and a control group. Secondly, whether patients were satisfied with their decision post-treatment was investigated. A prospective observational study was performed comparing patients with a superficial basal cell carcinoma who used a patient decision aid (patient decision aid group) with a control group. The primary outcome was the proportion of patients that chose non-invasive treatment. A secondary outcome was the mean score of "effective decision-making" on the Decisional Conflict Scale 3 months post-treatment. In the patient decision aid group, 48.6% (52/109) seemed to prefer non-invasive treatment vs 40.8% (42/103) in the control group (p = 0.255); the result was not significant. Three months post-treatment, the adjusted between-group mean difference in "effective decision-making" was -4.10 (p = 0.082) favouring the patient decision aid group (effect size 0.3). To conclude, patients who used a patient decision aid seemed to choose non-invasive therapy over surgery slightly more often but the result was not significant.

浅表基底细胞癌的手术或非侵入性治疗:患者的决定是否有助于做出个性化的治疗决定?
浅表性基底细胞癌患者可采用手术或非侵入性治疗,均具有特定的(非)优势。一项调查进行了是否偏爱手术或非侵入性治疗浅表性基底细胞癌的患者使用患者决策辅助和对照组之间的差异。其次,调查患者对治疗后的决定是否满意。一项前瞻性观察研究进行了比较浅表基底细胞癌患者使用患者决策辅助(患者决策辅助组)和对照组。主要结局是选择非侵入性治疗的患者比例。次要结果是治疗后3个月决策冲突量表“有效决策”的平均得分。在患者决策辅助组中,48.6%(52/109)倾向于非侵入性治疗,对照组40.8%(42/103)倾向于非侵入性治疗(p = 0.255);结果不显著。治疗后3个月,“有效决策”的调整组间平均差异为-4.10 (p = 0.082),有利于患者决策辅助组(效应量0.3)。综上所述,使用患者辅助决策的患者似乎比手术更常选择非侵入性治疗,但结果并不显著。
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来源期刊
Acta dermato-venereologica
Acta dermato-venereologica 医学-皮肤病学
CiteScore
4.90
自引率
2.80%
发文量
210
审稿时长
6-12 weeks
期刊介绍: Acta Dermato-Venereologica publishes high-quality manuscripts in English in the field of Dermatology and Venereology, dealing with new observations on basic dermatological and venereological research, as well as clinical investigations. Each volume also features a number of Review articles in special areas, as well as short Letters to the Editor to stimulate debate and to disseminate important clinical observations. Acta Dermato-Venereologica has rapid publication times and is amply illustrated with a large number of colour photographs.
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