Electrophilic thiocyanation of aromatic, heteroaromatic and aliphatic compounds: A novel perspective on recent advances

Abstract

One important technique in organic chemistry that makes it easier to create thiocyanate derivatives from aliphatic, aromatic and heteroaromatic molecules is electrophilic thiocyanation. In our earlier article, we explored the foundational concepts and approaches for synthesizing thiocyanates. This study offers a comprehensive and analytical review of the latest advancements in this field. We explore innovative trends, key drivers, and factors influencing the reaction conditions that have enhanced the yield and selectivity of these reactions. Additionally, we examine current research and present fresh ideas that weren't as prominent in our earlier work. Here, we shall categorize a broad range of techniques for the production of aromatic and heteroaromatic thiocyanate derivatives that have been developed over the last four years based on different catalysts. In addition to compiling the body of knowledge, this article helps scholars become acquainted with recent developments in electrophilic thiocyanation and pinpoint areas for further investigation.