Head and neck tumours with neuroendocrine marker ‘expression’: pitfalls and learning points

Diagnostic Histopathology Pub Date : 2025-04-01 DOI:10.1016/j.mpdhp.2025.02.004

Ella-Grace Kirton, Karwan Moutasim

引用次数: 0

Abstract

Poorly differentiated carcinomas can be a challenging area for histopathologists and frequently require ancillary tests to arrive at a definitive diagnosis. Neuroendocrine markers have the potential to be helpful in establishing a diagnosis but can also cause diagnostic dilemmas when aberrantly expressed. Here, we present three case examples to illustrate this issue and highlight relevant learning points in each case.

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头颈部肿瘤与神经内分泌标志物“表达”：陷阱和学习点

对于组织病理学家来说，低分化癌是一个具有挑战性的领域，经常需要辅助检查才能得到明确的诊断。神经内分泌标记物有可能有助于建立诊断，但当异常表达时也可能导致诊断困境。在这里，我们提供三个案例来说明这个问题，并强调每个案例中的相关学习点。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Diagnostic Histopathology Medicine-Pathology and Forensic Medicine

CiteScore

1.30

自引率

0.00%

发文量

期刊介绍： This monthly review journal aims to provide the practising diagnostic pathologist and trainee pathologist with up-to-date reviews on histopathology and cytology and related technical advances. Each issue contains invited articles on a variety of topics from experts in the field and includes a mini-symposium exploring one subject in greater depth. Articles consist of system-based, disease-based reviews and advances in technology. They update the readers on day-to-day diagnostic work and keep them informed of important new developments. An additional feature is the short section devoted to hypotheses; these have been refereed. There is also a correspondence section.