Implications of intrinsic capacity subtypes for post-PCI patients older than 45.

IF 3.9 2区综合性期刊 Q1 MULTIDISCIPLINARY SCIENCES

Scientific Reports Pub Date : 2025-04-05 DOI:10.1038/s41598-025-94485-1

Yuan Zhao, Yueying Jiang, Qunyan Xu, Dandan Chen, Panpan Tang, Xueqing Wang, Yunyu Guo, Chang Liu, Xiuqin Feng, Leiwen Tang

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Abstract

We aim to explore the contributing factors to intrinsic capacity (IC) in middle-aged and older patients after percutaneous coronary intervention (PCI). Intrinsic capacity comprises six core domains: cognition, locomotion, vitality, psychology, vision, and hearing. Each domain was assessed in detail using different scales, based on which the composite IC score was calculated. The study employed latent class analysis (LCA) to identify the various IC subtypes. Logistic regression analyses were used to determine the effect variables of IC subtypes. 318 middle-aged and older post-PCI patients filled out the assessments. Three distinct IC subtypes were found: 47.8% poor audition-vision group (class 1), 38% high cognition-psychology group (class 2), and 14.2% low locomotion-vitality group (class 3). The IC subtype classification may be impacted by factors such as cTnI, NT proBNP, cardiac function, exercise frequency, and comorbidities. Examining IC subtypes may be helpful for focused intervention, and further empirical research is still needed to determine their drivers.

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45岁以上pci术后患者内在容量亚型的意义。

我们的目的是探讨影响中老年患者经皮冠状动脉介入治疗（PCI）后内在容量（IC）的因素。内在能力包括六个核心领域：认知、运动、活力、心理、视觉和听觉。使用不同的量表对每个领域进行详细评估，并在此基础上计算综合IC分数。本研究采用潜类分析（LCA）来鉴定各种IC亚型。采用Logistic回归分析确定IC亚型的影响变量。318名中老年pci术后患者填写了评估。三种不同的IC亚型：47.8%的听力-视力差组（1类），38%的认知-心理高组（2类）和14.2%的运动-活力低组（3类）。IC亚型的分类可能受cTnI、NT proBNP、心功能、运动频率和合共病等因素的影响。检查IC亚型可能有助于集中干预，但仍需要进一步的实证研究来确定其驱动因素。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Scientific Reports Natural Science Disciplines-

CiteScore

7.50

自引率

4.30%

发文量

19567

审稿时长

3.9 months

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