The association between colonic diverticulosis and colorectal polyps in a retrospective cohort study.

IF 2.5 3区医学 Q2 GASTROENTEROLOGY & HEPATOLOGY

International Journal of Colorectal Disease Pub Date : 2025-04-05 DOI:10.1007/s00384-025-04866-1

Saygın Altıner, Yunushan Furkan Aydoğdu, Koray Kosmaz, Abdullah Durhan, Abdullah Senlikci, Marlen Suleyman, Can Ersak, Mevlüt Recep Pekcici

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Abstract

Objective: This study aimed to investigate the relationship between colonic diverticulosis, colorectal polyps, and colorectal cancer.

Material and methods: A total of 648 patients (275 females, 373 males) who underwent complete colonoscopy between January 2016 and June 2020 were retrospectively analyzed. The presence and localization of diverticula, polyps, and cancer were recorded, and the association between diverticular disease and the formation of polyps and cancer was evaluated.

Results: Diverticula were identified in 53 patients (8.2%), while 595 patients (91.8%) had no diverticula. Polyps were detected in 148 patients (22.8%), and no polyps were found in 500 patients (77.2%). Adenocarcinoma was diagnosed in 67 patients (10.3%), with no malignancy observed in 581 patients (89.7%). The mean age of patients with polyps was 59.5 years, compared to 53.3 years in those without polyps (p < 0.001). Multivariate logistic regression analysis revealed that diverticulum status did not significantly influence the risk of polyp formation, whereas advanced age was identified as a significant risk factor (p < 0.001).

Conclusion: Advanced age is a significant risk factor for colorectal polyp formation, whereas diverticulosis is not an independent risk factor. These findings highlight the importance of age-based screening strategies for colorectal neoplasia.

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一项回顾性队列研究：结肠憩室病与结肠息肉之间的关系。

目的：探讨结肠憩室病、结直肠息肉与结直肠癌的关系。材料和方法：回顾性分析2016年1月至2020年6月期间接受完整结肠镜检查的648例患者（女性275例，男性373例）。记录憩室、息肉和癌症的存在和定位，并评估憩室疾病与息肉和癌症形成之间的关系。结果：发现憩室53例（8.2%），未发现憩室595例（91.8%）。检出息肉148例（22.8%），未发现息肉500例（77.2%）。67例（10.3%）患者诊断为腺癌，581例（89.7%）患者未见恶性肿瘤。息肉患者的平均年龄为59.5岁，而无息肉患者的平均年龄为53.3岁(p)。结论：高龄是结直肠息肉形成的重要危险因素，而憩室病不是独立的危险因素。这些发现强调了基于年龄的结直肠肿瘤筛查策略的重要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

International Journal of Colorectal Disease 医学-外科

CiteScore

4.90

自引率

3.60%

发文量

206

审稿时长

3-8 weeks

期刊介绍： The International Journal of Colorectal Disease, Clinical and Molecular Gastroenterology and Surgery aims to publish novel and state-of-the-art papers which deal with the physiology and pathophysiology of diseases involving the entire gastrointestinal tract. In addition to original research articles, the following categories will be included: reviews (usually commissioned but may also be submitted), case reports, letters to the editor, and protocols on clinical studies. The journal offers its readers an interdisciplinary forum for clinical science and molecular research related to gastrointestinal disease.