Advancing Upper Gastrointestinal Cancer Detection: A Single-Center Pilot Study Exploring the Potential of Electrical Impedance Spectroscopy in Endoscopic Procedures.

IF 2.5 4区医学 Q2 GASTROENTEROLOGY & HEPATOLOGY

Digestive Diseases and Sciences Pub Date : 2025-04-05 DOI:10.1007/s10620-025-08983-3

Hadi Mokhtari Dowlatabad, Reihane Mahdavi, Seyed Rouhollah Miri, Mohammad Reza Fattahi, Hossein Ataee, Narges Yousefpour, Navid Manoochehri, Reza Taslimi, Mohammad Abdolahad

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引用次数: 0

Abstract

Purpose: Early detection of GI cancer mass is of utmost importance due to the risks of misdiagnoses that occur through standard endoscopic evaluation.

Methods: In this research, a real-time intra-endoscopic electrical diagnostic probe has been introduced to discriminate high-risk excision-required lesions utilizing a modified endoscopic biopsy forceps as a non-invasive method.

Results: By testing on 52 patients who had undergone endoscopic biopsy with a total of 18 high-risk lesions, the invented device named Electrical Endoscopic Mass Characterizer (EEMC), showed %94.7 sensitivity, %93.9 specificity, and %94.2 accuracy (p < 0.01) based on histopathological evaluations of removed specimens as the gold standard.

Conclusions: EEMC can be utilized as a precise complementary device during endoscopic evaluation for improving the accuracy of early-stage GI cancer detection with no interruptions in the routine procedure.

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来源期刊

Digestive Diseases and Sciences 医学-胃肠肝病学

CiteScore

6.40

自引率

3.20%

发文量

420

审稿时长

1 months

期刊介绍： Digestive Diseases and Sciences publishes high-quality, peer-reviewed, original papers addressing aspects of basic/translational and clinical research in gastroenterology, hepatology, and related fields. This well-illustrated journal features comprehensive coverage of basic pathophysiology, new technological advances, and clinical breakthroughs; insights from prominent academicians and practitioners concerning new scientific developments and practical medical issues; and discussions focusing on the latest changes in local and worldwide social, economic, and governmental policies that affect the delivery of care within the disciplines of gastroenterology and hepatology.