A validation study of the Intentional Nonadherence Scale among people with type 2 diabetes in the United Kingdom.

IF 3.2 3区 医学 Q2 ENDOCRINOLOGY & METABOLISM
Vivien Teo, Anna Hodgkinson, John Weinman, Mark Chamley, Kai Zhen Yap
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Abstract

Aim: To examine the psychometric properties of the Intentional Nonadherence Scale (INAS) among people with type 2 diabetes mellitus (PwT2D) in the United Kingdom.

Methods: This validation study recruited 260 PwT2D at diabetes intermediate care team clinics in London. Thirty of them participated in the test-retest reliability analysis in 2-4 weeks, while 124 were followed up in 3-6 months for the predictive validity analysis. The psychometric evaluation also comprised internal reliability, structural validity and construct validity that assessed the relationship between the INAS and other established measures, such as the Medication Adherence Report Scale-5 (MARS-5), Beliefs about Medicine Questionnaire (BMQ)-specific, Brief Illness Perception Questionnaire (BIPQ), Patient Health Questionnaire-2 (PHQ-2) and glycated haemoglobin (HbA1c).

Results: Exploratory factor analysis revealed four factors, namely 'Resisting illness', 'Resisting medication', 'Testing treatment' and 'Sensitivity to medication'. All INAS factors demonstrated high internal reliability (Cronbach's alpha = 0.92-0.96). Their test-retest reliability varied between <0.001 and 0.92. Construct validity was demonstrated by its relationship with other measures, including its negative correlations with medication adherence and positive correlations with medication concerns. Significant correlations were also found with HbA1c, as well as with PwT2D's perceptions of diabetes consequences, treatment control, identity and emotional responses to diabetes. 'Testing Treatment' showed a trend towards statistical significance with adherence in 3-6 months (coefficient = -0.34, p = 0.09).

Conclusions: The INAS performed well on a number of psychometric properties in this study. It may be a helpful tool for clinicians in identifying specific drivers of intentional nonadherence among PwT2D.

英国2型糖尿病患者故意不依从性量表的验证研究
目的:研究英国2型糖尿病(PwT2D)患者故意不依从性量表(INAS)的心理测量特征。方法:本验证性研究在伦敦的糖尿病中间护理团队诊所招募了260名PwT2D患者。其中30人在2-4周内进行重测信度分析,124人在3-6个月内进行预测效度分析。心理测量评估还包括内部信度、结构效度和结构效度,以评估INAS与其他既定测量之间的关系,如药物依从性报告量表-5 (MARS-5)、药物信念问卷(BMQ)特异性、简短疾病感知问卷(BIPQ)、患者健康问卷-2 (PHQ-2)和糖化血红蛋白(HbA1c)。结果:探索性因素分析揭示了“抗病”、“耐药”、“试验治疗”和“药物敏感性”四个因素。所有INAS因子均具有较高的内部信度(Cronbach's alpha = 0.92-0.96)。结论:在本研究中,INAS在许多心理测量特性上表现良好。这可能是临床医生识别PwT2D患者故意不依从的特定驱动因素的有用工具。
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来源期刊
Diabetic Medicine
Diabetic Medicine 医学-内分泌学与代谢
CiteScore
7.20
自引率
5.70%
发文量
229
审稿时长
3-6 weeks
期刊介绍: Diabetic Medicine, the official journal of Diabetes UK, is published monthly simultaneously, in print and online editions. The journal publishes a range of key information on all clinical aspects of diabetes mellitus, ranging from human genetic studies through clinical physiology and trials to diabetes epidemiology. We do not publish original animal or cell culture studies unless they are part of a study of clinical diabetes involving humans. Categories of publication include research articles, reviews, editorials, commentaries, and correspondence. All material is peer-reviewed. We aim to disseminate knowledge about diabetes research with the goal of improving the management of people with diabetes. The journal therefore seeks to provide a forum for the exchange of ideas between clinicians and researchers worldwide. Topics covered are of importance to all healthcare professionals working with people with diabetes, whether in primary care or specialist services. Surplus generated from the sale of Diabetic Medicine is used by Diabetes UK to know diabetes better and fight diabetes more effectively on behalf of all people affected by and at risk of diabetes as well as their families and carers.”
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