Multimodal therapy successfully treats methemoglobinemia caused by emamectin benzoate and indoxacarb poisoning: a case report.

IF 2.4 3区医学 Q2 PATHOLOGY

Diagnostic Pathology Pub Date : 2025-04-05 DOI:10.1186/s13000-025-01634-1

Qun Zhang, Yun-Yang Luan, Fei-Fei Sun, Yong-Qiang Chen, Shuang-de Wang, Guang-Wen Hu

引用次数: 0

Abstract

Poisoning from emamectin benzoate combined with indoxacarb can cause neurological symptoms and methemoglobinemia, which may present clinically as confusion, cyanosis, dyspnea, and limb convulsions. In such cases, naloxone can be used to alleviate neurological symptoms, while high-dose vitamin C and low-concentration methylene blue can reduce methemoglobin (MetHb) to improve hypoxic symptoms. Hemoperfusion and continuous renal replacement therapy (CRRT) can rapidly remove exogenous and endogenous toxins from the blood, effectively protecting against organ damage to the heart, liver, and kidneys caused by emamectin benzoate poisoning.

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来源期刊

Diagnostic Pathology 医学-病理学

CiteScore

4.60

自引率

0.00%

发文量

审稿时长

1 months

期刊介绍： Diagnostic Pathology is an open access, peer-reviewed, online journal that considers research in surgical and clinical pathology, immunology, and biology, with a special focus on cutting-edge approaches in diagnostic pathology and tissue-based therapy. The journal covers all aspects of surgical pathology, including classic diagnostic pathology, prognosis-related diagnosis (tumor stages, prognosis markers, such as MIB-percentage, hormone receptors, etc.), and therapy-related findings. The journal also focuses on the technological aspects of pathology, including molecular biology techniques, morphometry aspects (stereology, DNA analysis, syntactic structure analysis), communication aspects (telecommunication, virtual microscopy, virtual pathology institutions, etc.), and electronic education and quality assurance (for example interactive publication, on-line references with automated updating, etc.).