A study on dermatologists’ self-assessment of the efficacy of a 1% selenium disulfide—0.9% salicylic acid -based shampoo for scalp seborrheic dermatitis

IF 1.8 4区医学 Q3 DERMATOLOGY

Archives of Dermatological Research Pub Date : 2025-04-07 DOI:10.1007/s00403-025-04165-3

Xi Chen, Jiaxin Li, Yurong Li, Aihua Wei

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Abstract

Scalp seborrheic dermatitis (SSD) is a common inflammatory condition requiring effective topical treatment options. To evaluate the efficacy and acceptability of a 1% selenium disulfide (SeS2)-0.9% salicylic acid shampoo in treating mild to moderate SSD among dermatologists. 95 dermatologists with mild to moderate SSD used the shampoo thrice weekly for 4 weeks. Symptoms were assessed using Visual Analog Scale (VAS) at baseline, Day 14, and Day 28. After 4-week treatment, severe dandruff cases decreased from 28.4% to 3.2%, with 90.5% participants reporting only mild or no dandruff. VAS scores showed significant improvement in all symptoms (p < 0.01). Product satisfaction reached 88.5%, with 90.5% willing to recommend it clinically. The findings of this study suggest that a shampoo based on 1% selenium disulfide (SeS2) and 0.9% salicylic acid is effective in helping alleviate the symptoms of seborrheic dermatitis (SSD).

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皮肤科医生对1%二硫化硒- 0.9%水杨酸洗发水治疗头皮脂溢性皮炎疗效的自我评价研究

头皮脂溢性皮炎（SSD）是一种常见的炎症条件，需要有效的局部治疗方案。目的：评价1%二硫化硒(SeS2)-0.9%水杨酸洗发水治疗轻至中度SSD的疗效和可接受性。95名患有轻度至中度SSD的皮肤科医生每周使用三次洗发水，持续4周。在基线、第14天和第28天使用视觉模拟量表（VAS）评估症状。经过4周的治疗，严重头皮屑病例从28.4%下降到3.2%，90.5%的参与者报告只有轻微或没有头皮屑。VAS评分显示所有症状均有显著改善（p < 0.01）。产品满意度达88.5%，90.5%愿意临床推荐。本研究结果表明，基于1%二硫化硒（SeS2）和0.9%水杨酸的洗发水可以有效缓解脂溢性皮炎（SSD）的症状。

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来源期刊

Archives of Dermatological Research 医学-皮肤病学

CiteScore

4.10

自引率

3.30%

发文量

审稿时长

4-8 weeks

期刊介绍： Archives of Dermatological Research is a highly rated international journal that publishes original contributions in the field of experimental dermatology, including papers on biochemistry, morphology and immunology of the skin. The journal is among the few not related to dermatological associations or belonging to respective societies which guarantees complete independence. This English-language journal also offers a platform for review articles in areas of interest for dermatologists and for publication of innovative clinical trials.