Microfluidic Construction of Heterogeneous Micro–Nano-Structured Materials for Biomedical Applications

IF 9.6 1区化学 Q1 MATERIALS SCIENCE, MULTIDISCIPLINARY

ACS Materials Letters Pub Date : 2025-03-20 DOI:10.1021/acsmaterialslett.4c0248710.1021/acsmaterialslett.4c02487

Xiaowei Yang, Chaojing Li*, Yongjie Jiao, Lu Wang and Fujun Wang*,

引用次数: 0

Abstract

This review focuses on the use of microfluidic technology for the fabrication of heterogeneous micro–nano-structured materials, with an emphasis on anisotropic structures shaped by hydrodynamic conditions. Microfluidics allows precise control over fluid flow, enabling the creation of materials with tailored size, shape, and composition at the microscale. Through the manipulation of parameters such as flow rate, viscosity, and surface tension, it is possible to produce complex heterogeneous micro–nano structures with varying functional properties. These materials are particularly promising for biomedical applications including cell culture, drug delivery, tissue engineering, and in vitro models. The review also addresses the challenges and future directions in the field, highlighting the potential for microfluidic technology to advance biomedical research, personalized medicine, and regenerative therapies.

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生物医学应用非均质微纳米结构材料的微流控构建

本文综述了利用微流体技术制备非均质微纳米结构材料，重点介绍了流体动力条件下形成的各向异性结构。微流体允许对流体流动进行精确控制，从而能够在微尺度上创建具有定制尺寸，形状和成分的材料。通过控制流速、粘度和表面张力等参数，可以制备出具有不同功能特性的复杂非均相微纳结构。这些材料在生物医学应用方面尤其有前景，包括细胞培养、药物输送、组织工程和体外模型。该综述还讨论了该领域的挑战和未来方向，强调了微流体技术在推进生物医学研究、个性化医疗和再生治疗方面的潜力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

ACS Materials Letters MATERIALS SCIENCE, MULTIDISCIPLINARY-

CiteScore

14.60

自引率

3.50%

发文量

261

期刊介绍： ACS Materials Letters is a journal that publishes high-quality and urgent papers at the forefront of fundamental and applied research in the field of materials science. It aims to bridge the gap between materials and other disciplines such as chemistry, engineering, and biology. The journal encourages multidisciplinary and innovative research that addresses global challenges. Papers submitted to ACS Materials Letters should clearly demonstrate the need for rapid disclosure of key results. The journal is interested in various areas including the design, synthesis, characterization, and evaluation of emerging materials, understanding the relationships between structure, property, and performance, as well as developing materials for applications in energy, environment, biomedical, electronics, and catalysis. The journal has a 2-year impact factor of 11.4 and is dedicated to publishing transformative materials research with fast processing times. The editors and staff of ACS Materials Letters actively participate in major scientific conferences and engage closely with readers and authors. The journal also maintains an active presence on social media to provide authors with greater visibility.