A systematic review on cellulose based hydrogels for anti-microbial applications

IF 4.9 2区工程技术 Q1 MATERIALS SCIENCE, PAPER & WOOD

Cellulose Pub Date : 2025-03-04 DOI:10.1007/s10570-025-06435-9

Gaurav Sharma, Yaksha Verma, Amit Kumar, Pooja Dhiman, F. J. Stadler

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引用次数: 0

Abstract

Cellulose-based hydrogels have garnered significant interest in antimicrobial applications due to their exceptional biocompatibility, biodegradability, and superior mechanical properties. This in-depth investigation explores the various mechanisms and innovative strategies employed by cellulose-based hydrogels to exhibit remarkable antimicrobial activity. Our review aims to provide significant insights into utilizing the full potential of cellulose sources, cross-linking moieties, and polymerization processes on the structure, porosity, and mechanical properties of hydrogels by highlighting the major features and recent advancements in this developing sector. Additionally, we examine alternative functionalization methods for enhancing antimicrobial efficacy, such as incorporating antimicrobial moieties and surface modification. Understanding the mechanisms of action that disrupt microbial cell membranes and cell walls is crucial for comprehending their antimicrobial efficacy. Moreover, we assess the antimicrobial action of these hydrogels against various pathogens, including fungi and bacteria. Finally, we address recent achievements and future goals in this field, emphasizing the importance of continued research and collaboration. This demonstrates the potential of cellulose-based hydrogels as potent weapons in the battle against antimicrobial resistance.

Graphical Abstract

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来源期刊

Cellulose 工程技术-材料科学：纺织

CiteScore

10.10

自引率

10.50%

发文量

580

审稿时长

3-8 weeks

期刊介绍： Cellulose is an international journal devoted to the dissemination of research and scientific and technological progress in the field of cellulose and related naturally occurring polymers. The journal is concerned with the pure and applied science of cellulose and related materials, and also with the development of relevant new technologies. This includes the chemistry, biochemistry, physics and materials science of cellulose and its sources, including wood and other biomass resources, and their derivatives. Coverage extends to the conversion of these polymers and resources into manufactured goods, such as pulp, paper, textiles, and manufactured as well natural fibers, and to the chemistry of materials used in their processing. Cellulose publishes review articles, research papers, and technical notes.