Facial Skin Aging: Effect of Aging in Different Layers of the Skin on Wrinkles and Sagging

IF 2 3区物理与天体物理 Q3 BIOCHEMICAL RESEARCH METHODS

Journal of Biophotonics Pub Date : 2025-04-03 DOI:10.1002/jbio.70028

Dangdang Cheng, Qin Zhang, Wanwen Shan, Feifei Wang

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引用次数: 0

Abstract

Objective

To investigate the impact of aging in different skin layers on the formation of wrinkles and sagging.

Methods

In a single-center clinical study, the skin micromorphology, wrinkles, and sagging of 34 participants aged 42–60 years who use an antiaging product for 56 days are discussed retrospectively and observationally. The variation trend of each parameter and the correlation between micromorphology parameters and wrinkles and sagging are analyzed.

Results

Parameters related to epidermal aging show a strong correlation with wrinkles and sagging, whereas parameters related to dermal aging show no significant correlation with wrinkles and sagging; in addition, parameters related to the dermal–epidermal junction (DEJ) show a moderate correlation with wrinkles and sagging.

Conclusion

For individuals in the rapid and stable aging phases, aging of the epidermis has a greater impact on wrinkles and sagging than aging of the dermis and DEJ.

Abstract Image

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面部皮肤老化：不同皮肤层的老化对皱纹和松弛的影响。

目的：探讨不同皮肤层老化对皱纹和松弛形成的影响。方法：在一项单中心临床研究中，回顾性观察了34名年龄在42-60岁的参与者使用抗衰老产品56天后的皮肤微观形态、皱纹和下垂。分析了各参数的变化趋势以及微观形貌参数与起皱、下垂的相关性。结果：表皮老化相关参数与皱纹、下垂有较强的相关性，而真皮老化相关参数与皱纹、下垂无显著相关性；此外，与真皮-表皮交界处（DEJ）相关的参数显示与皱纹和下垂有适度的相关性。结论：对于处于快速和稳定衰老阶段的个体，表皮衰老对皱纹和松弛的影响大于真皮层和DEJ的衰老。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Biophotonics 生物-生化研究方法

CiteScore

5.70

自引率

7.10%

发文量

248

审稿时长

1 months

期刊介绍： The first international journal dedicated to publishing reviews and original articles from this exciting field, the Journal of Biophotonics covers the broad range of research on interactions between light and biological material. The journal offers a platform where the physicist communicates with the biologist and where the clinical practitioner learns about the latest tools for the diagnosis of diseases. As such, the journal is highly interdisciplinary, publishing cutting edge research in the fields of life sciences, medicine, physics, chemistry, and engineering. The coverage extends from fundamental research to specific developments, while also including the latest applications.