Tia Rudman, Richard S Rowlands, Jorgen S Jensen, Michael L Beeton, On Behalf Of The Escmid Study Group For Mycoplasma And Chlamydia Infections Esgmac
{"title":"JMM Profile: <i>Mycoplasma genitalium</i>: a small, yet significant pathogen.","authors":"Tia Rudman, Richard S Rowlands, Jorgen S Jensen, Michael L Beeton, On Behalf Of The Escmid Study Group For Mycoplasma And Chlamydia Infections Esgmac","doi":"10.1099/jmm.0.001984","DOIUrl":null,"url":null,"abstract":"<p><p><i>Mycoplasma genitalium</i> is characterized by a small genome and a lack of a cell wall, contributing to its unique biology. It is associated with reproductive tract infections, including non-gonococcal urethritis and pelvic inflammatory disease. It is nearly as common as chlamydia in most studies from high-income countries. The emergence of antimicrobial resistance in <i>M. genitalium</i> raises concern about the long-term efficacy of current therapeutic strategies. Understanding its genomic intricacies and pathogenic mechanisms is crucial for developing targeted interventions to address the growing public health impact of this elusive microbe.</p>","PeriodicalId":94093,"journal":{"name":"Journal of medical microbiology","volume":"74 4","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of medical microbiology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1099/jmm.0.001984","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
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Abstract
Mycoplasma genitalium is characterized by a small genome and a lack of a cell wall, contributing to its unique biology. It is associated with reproductive tract infections, including non-gonococcal urethritis and pelvic inflammatory disease. It is nearly as common as chlamydia in most studies from high-income countries. The emergence of antimicrobial resistance in M. genitalium raises concern about the long-term efficacy of current therapeutic strategies. Understanding its genomic intricacies and pathogenic mechanisms is crucial for developing targeted interventions to address the growing public health impact of this elusive microbe.
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