The burden of brucellosis in donkeys and its implications for public health and animal welfare: A systematic review and meta-analysis.

IF 1.7 Q2 AGRICULTURE, DAIRY & ANIMAL SCIENCE
Veterinary World Pub Date : 2025-02-01 Epub Date: 2025-02-17 DOI:10.14202/vetworld.2025.367-378
James Mutiiria Kithuka, Timothy Muthui Wachira, Joshua Orungo Onono, Wyckliff Ngetich
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Abstract

Background and aim: Brucellosis is a globally significant zoonotic disease affecting a wide range of wild and domestic animals, with implications for human and animal health. Despite donkeys' crucial roles in agriculture, transportation, and livelihoods, there is limited research on the burden of brucellosis in this species. This study systematically reviews the prevalence and role of donkeys as reservoirs for Brucella spp., providing insights into their public health implications.

Materials and methods: Using the PRISMA guidelines, a systematic search of PubMed, Scopus, and Google Scholar was conducted for studies published from 1990 to May 2024. Out of 1159 retrieved articles, 20 met the inclusion criteria. Data on study design, location, diagnostic methods, and brucellosis prevalence were extracted and analyzed using R statistical software. Pooled prevalence and heterogeneity were calculated, and the Newcastle-Ottawa Scale was employed to assess study quality.

Results: The pooled prevalence of brucellosis in 6785 donkeys across 20 studies was 10.23% (range: 0%-63.7%), with the highest prevalence reported in Asia (26.80%). While 15% of studies suggested that donkeys act as reservoirs for Brucella spp., direct evidence linking donkeys to disease transmission remains scarce. The disease's impact on donkey reproduction, including abortion and infertility, is underexplored, highlighting a significant research gap.

Conclusion: Brucellosis in donkeys represents a notable zoonotic and occupational risk. The limited data from East Africa, despite its high donkey population, emphasize the need for comprehensive epidemiological studies. Findings underscore the importance of targeted interventions, including biosecurity, public education, and enhanced diagnostic approaches, to mitigate brucellosis' impact on donkey health and its broader public health implications.

驴的布鲁氏菌病负担及其对公共卫生和动物福利的影响:系统回顾和荟萃分析。
背景和目的:布鲁氏菌病是一种全球重要的人畜共患疾病,影响广泛的野生动物和家畜,对人类和动物健康产生影响。尽管驴在农业、交通和生计中发挥着至关重要的作用,但对这一物种的布鲁氏菌病负担的研究有限。本研究系统地回顾了驴作为布鲁氏菌宿主的流行和作用,为其公共卫生影响提供了见解。材料和方法:使用PRISMA指南,系统检索PubMed, Scopus和谷歌Scholar,检索1990年至2024年5月发表的研究。在1159篇检索文章中,有20篇符合纳入标准。提取研究设计、地点、诊断方法和布鲁氏菌病患病率的数据,并使用R统计软件进行分析。计算合并患病率和异质性,并采用纽卡斯尔-渥太华量表评估研究质量。结果:在20项研究中,6785头驴的布鲁氏菌病总患病率为10.23%(范围:0%-63.7%),其中亚洲报告的患病率最高(26.80%)。虽然15%的研究表明驴是布鲁氏菌的宿主,但将驴与疾病传播联系起来的直接证据仍然很少。该疾病对驴繁殖的影响,包括流产和不育,尚未得到充分探讨,突出了一个重大的研究空白。结论:驴子的布鲁氏菌病具有显著的人畜共患和职业风险。来自东非的有限数据,尽管其驴子数量众多,强调需要进行全面的流行病学研究。研究结果强调了有针对性的干预措施的重要性,包括生物安全、公共教育和改进的诊断方法,以减轻布鲁氏菌病对驴健康的影响及其更广泛的公共卫生影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Veterinary World
Veterinary World Multiple-
CiteScore
3.60
自引率
12.50%
发文量
317
审稿时长
16 weeks
期刊介绍: Veterinary World publishes high quality papers focusing on Veterinary and Animal Science. The fields of study are bacteriology, parasitology, pathology, virology, immunology, mycology, public health, biotechnology, meat science, fish diseases, nutrition, gynecology, genetics, wildlife, laboratory animals, animal models of human infections, prion diseases and epidemiology. Studies on zoonotic and emerging infections are highly appreciated. Review articles are highly appreciated. All articles published by Veterinary World are made freely and permanently accessible online. All articles to Veterinary World are posted online immediately as they are ready for publication.
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