A systematic review of SARS-CoV-2 associated sudden onset sensorineural hearing loss.

IF 0.8 4区医学 Q3 OTORHINOLARYNGOLOGY

Journal of Laryngology and Otology Pub Date : 2025-04-04 DOI:10.1017/S002221512500026X

Maisie Fouweather, Benjamin Talks, Nicholas Dawe, Michael Mather

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引用次数: 0

Abstract

Objectives: Sudden onset sensorineural hearing loss has been associated with infection by severe acute respiratory syndrome coronavirus-2. However, little is known regarding how this differs from sudden onset sensorineural hearing loss of other aetiologies. This systematic review summarises existing literature on severe acute respiratory syndrome coronavirus-2 associated sudden onset sensorineural hearing loss treatment and outcomes.

Methods: A literature search using Ovid was performed for studies which evaluated treatments and outcomes of patients with sudden onset sensorineural hearing loss associated with severe acute respiratory syndrome coronavirus-2 infection.

Results: A total of 99 studies were identified, from which 14 studies were selected for inclusion - collectively including 154 patients. Nine of these studies were single participant case reports and five were larger case series. Corticosteroid treatment varied between studies in terms of administration route, dose, and duration. Only 63/154 patients in this review achieved complete resolution of their symptoms following steroid treatment.

Conclusion: Oral, intravenous, and intratympanic steroids demonstrate a good safety profile. However, the majority of patients are left with unresolved hearing loss.

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与 SARS-CoV-2 相关的突发性感音神经性听力损失的系统回顾。

目的：突发性感音神经性听力损失与严重急性呼吸综合征冠状病毒-2感染有关。然而，关于这与其他病因的突发性感音神经性听力损失有何不同，人们知之甚少。本系统综述了现有的关于严重急性呼吸综合征冠状病毒2相关的突发性感音神经性听力损失治疗和结果的文献。方法：采用Ovid软件对重症急性呼吸综合征冠状病毒-2感染并发突发性感音神经性听力损失患者的治疗方法和预后进行文献检索。结果：共纳入99项研究，其中14项研究入选，共纳入154例患者。这些研究中有9项是单参与者病例报告，5项是更大的病例系列。不同研究的皮质类固醇治疗在给药途径、剂量和持续时间方面存在差异。在本综述中，只有63/154的患者在类固醇治疗后症状完全缓解。结论：口服、静脉注射和鼓内注射类固醇具有良好的安全性。然而，大多数患者的听力损失仍未得到解决。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Laryngology and Otology 医学-耳鼻喉科学

CiteScore

3.20

自引率

11.80%

发文量

593

审稿时长

3-6 weeks

期刊介绍： The Journal of Laryngology & Otology (JLO) is a leading, monthly journal containing original scientific articles and clinical records in otology, rhinology, laryngology and related specialties. Founded in 1887, JLO is absorbing reading for ENT specialists and trainees. The journal has an international outlook with contributions from around the world, relevant to all specialists in this area regardless of the country in which they practise. JLO contains main articles (original, review and historical), case reports and short reports as well as radiology, pathology or oncology in focus, a selection of abstracts, book reviews, letters to the editor, general notes and calendar, operative surgery techniques, and occasional supplements. It is fully illustrated and has become a definitive reference source in this fast-moving subject area. Published monthly an annual subscription is excellent value for money. Included in the subscription is access to the JLO interactive web site with searchable abstract database of the journal archive back to 1887.