Emil Hyldahl, Henning Schliephake, Simon Storgård Jensen
{"title":"Dental Implant Therapy in Patients With Autoimmune Diseases: A Scoping Review.","authors":"Emil Hyldahl, Henning Schliephake, Simon Storgård Jensen","doi":"10.1111/clr.14440","DOIUrl":null,"url":null,"abstract":"<p><strong>Objectives: </strong>The aim of this scoping review is to determine the effects of autoimmune diseases (ADs) and the agents used for treatment on dental implant survival and biologic outcomes.</p><p><strong>Material and methods: </strong>An electronic database search was performed in MEDLINE (PubMed), The Cochrane Library, and Embase on 29-04-2024. Clinical studies in English on implant therapy in patients with ADs were potentially eligible. Recorded variables included study information, patient demographics, ADs, immunosuppressants, antiresorptives, dental implant survival rate, biologic complications, and oral health-related quality of life. Descriptive statistics were performed.</p><p><strong>Results: </strong>A total of 6319 records were retrieved through database search and hand search, of which 87 studies could be included with an overweight of case reports and retrospective studies. The available evidence was characterized by a high number of studies placed low on the hierarchy of evidence. Several outcome parameters were heterogeneously reported. Glucocorticoids were the most frequently administrated immunosuppressant. The implant survival rate was overall 85.3%-100%; hereof, 46.7%-100% of implant losses occurred early, indicating a certain risk of implant failure. Despite high implant survival in oral lichen planus (OLP) patients, one study lost 42 of 55 implants in patients with untreated flare-up of OLP.</p><p><strong>Conclusions: </strong>Dental implant treatment is generally predictable with a high implant survival rate, after mid-term follow-up, in patients with ADs, of whom many receive immunosuppressants. Implant losses occurred predominantly before prosthetic loading. Particularly, patients with mucosal manifestations of their ADs seem to benefit from implant-supported restorations provided mucosal lesions are well treated. However, overall low-level scientific evidence was available.</p>","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":" ","pages":""},"PeriodicalIF":4.8000,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Oral Implants Research","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.1111/clr.14440","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"DENTISTRY, ORAL SURGERY & MEDICINE","Score":null,"Total":0}
引用次数: 0
Abstract
Objectives: The aim of this scoping review is to determine the effects of autoimmune diseases (ADs) and the agents used for treatment on dental implant survival and biologic outcomes.
Material and methods: An electronic database search was performed in MEDLINE (PubMed), The Cochrane Library, and Embase on 29-04-2024. Clinical studies in English on implant therapy in patients with ADs were potentially eligible. Recorded variables included study information, patient demographics, ADs, immunosuppressants, antiresorptives, dental implant survival rate, biologic complications, and oral health-related quality of life. Descriptive statistics were performed.
Results: A total of 6319 records were retrieved through database search and hand search, of which 87 studies could be included with an overweight of case reports and retrospective studies. The available evidence was characterized by a high number of studies placed low on the hierarchy of evidence. Several outcome parameters were heterogeneously reported. Glucocorticoids were the most frequently administrated immunosuppressant. The implant survival rate was overall 85.3%-100%; hereof, 46.7%-100% of implant losses occurred early, indicating a certain risk of implant failure. Despite high implant survival in oral lichen planus (OLP) patients, one study lost 42 of 55 implants in patients with untreated flare-up of OLP.
Conclusions: Dental implant treatment is generally predictable with a high implant survival rate, after mid-term follow-up, in patients with ADs, of whom many receive immunosuppressants. Implant losses occurred predominantly before prosthetic loading. Particularly, patients with mucosal manifestations of their ADs seem to benefit from implant-supported restorations provided mucosal lesions are well treated. However, overall low-level scientific evidence was available.
期刊介绍：
Clinical Oral Implants Research conveys scientific progress in the field of implant dentistry and its related areas to clinicians, teachers and researchers concerned with the application of this information for the benefit of patients in need of oral implants. The journal addresses itself to clinicians, general practitioners, periodontists, oral and maxillofacial surgeons and prosthodontists, as well as to teachers, academicians and scholars involved in the education of professionals and in the scientific promotion of the field of implant dentistry.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
