Acute Toxicity of 4-HDPA and 6PPDQ, transformation products of 6PPD, to early instars of the mayfly, Neocloeon triangulifer.

IF 3.6 4区环境科学与生态学 Q2 ENVIRONMENTAL SCIENCES

Environmental Toxicology and Chemistry Pub Date : 2025-04-03 DOI:10.1093/etojnl/vgaf062

David J Soucek, Rebecca A Dorman, Jeffery A Steevens, Viviane Yargeau, Marco Pineda, Erin R Bennett, Christopher D Metcalfe

{"title":"Acute Toxicity of 4-HDPA and 6PPDQ, transformation products of 6PPD, to early instars of the mayfly, Neocloeon triangulifer.","authors":"David J Soucek, Rebecca A Dorman, Jeffery A Steevens, Viviane Yargeau, Marco Pineda, Erin R Bennett, Christopher D Metcalfe","doi":"10.1093/etojnl/vgaf062","DOIUrl":null,"url":null,"abstract":"<p><p>Our analysis of water samples collected during a rain event from two urban rivers in the Greater Toronto Area, Ontario, Canada indicated that selected transformation products (TPs) of the tire antioxidant, 6PPD, including 6PPD-quinone (6PPDQ) and 4-hydroxydiphenylamine (4-HDPA) were present at concentrations >1 µg/L. In acute (96-h) toxicity tests with aquatic larvae of the mayfly, Neocloeon triangulifer, 6PPDQ did not cause mortalities at the highest test concentration, which was just below the limit of solubility. In toxicity tests with 4-HDPA, a calculated 96-h LC50 of 339 µg/L is above environmentally relevant concentrations. However, in toxicity tests with 6PPD, there was evidence that the degradation of this tire wear compound produced unknown TPs that caused mortalities in exposed mayfly larvae. Additional work could identify other TPs of 6PPD that could be a hazard to aquatic invertebrates exposed to tire wear compounds transported into surface waters from transportation corridors.</p>","PeriodicalId":11793,"journal":{"name":"Environmental Toxicology and Chemistry","volume":" ","pages":""},"PeriodicalIF":3.6000,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Environmental Toxicology and Chemistry","FirstCategoryId":"93","ListUrlMain":"https://doi.org/10.1093/etojnl/vgaf062","RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ENVIRONMENTAL SCIENCES","Score":null,"Total":0}

引用次数: 0

Abstract

Our analysis of water samples collected during a rain event from two urban rivers in the Greater Toronto Area, Ontario, Canada indicated that selected transformation products (TPs) of the tire antioxidant, 6PPD, including 6PPD-quinone (6PPDQ) and 4-hydroxydiphenylamine (4-HDPA) were present at concentrations >1 µg/L. In acute (96-h) toxicity tests with aquatic larvae of the mayfly, Neocloeon triangulifer, 6PPDQ did not cause mortalities at the highest test concentration, which was just below the limit of solubility. In toxicity tests with 4-HDPA, a calculated 96-h LC50 of 339 µg/L is above environmentally relevant concentrations. However, in toxicity tests with 6PPD, there was evidence that the degradation of this tire wear compound produced unknown TPs that caused mortalities in exposed mayfly larvae. Additional work could identify other TPs of 6PPD that could be a hazard to aquatic invertebrates exposed to tire wear compounds transported into surface waters from transportation corridors.

查看原文本刊更多论文

求助全文

约1分钟内获得全文求助全文

来源期刊

Environmental Toxicology and Chemistry 环境科学-毒理学

CiteScore

7.40

自引率

9.80%

发文量

265

审稿时长

3.4 months

期刊介绍： The Society of Environmental Toxicology and Chemistry (SETAC) publishes two journals: Environmental Toxicology and Chemistry (ET&C) and Integrated Environmental Assessment and Management (IEAM). Environmental Toxicology and Chemistry is dedicated to furthering scientific knowledge and disseminating information on environmental toxicology and chemistry, including the application of these sciences to risk assessment.[...] Environmental Toxicology and Chemistry is interdisciplinary in scope and integrates the fields of environmental toxicology; environmental, analytical, and molecular chemistry; ecology; physiology; biochemistry; microbiology; genetics; genomics; environmental engineering; chemical, environmental, and biological modeling; epidemiology; and earth sciences. ET&C seeks to publish papers describing original experimental or theoretical work that significantly advances understanding in the area of environmental toxicology, environmental chemistry and hazard/risk assessment. Emphasis is given to papers that enhance capabilities for the prediction, measurement, and assessment of the fate and effects of chemicals in the environment, rather than simply providing additional data. The scientific impact of papers is judged in terms of the breadth and depth of the findings and the expected influence on existing or future scientific practice. Methodological papers must make clear not only how the work differs from existing practice, but the significance of these differences to the field. Site-based research or monitoring must have regional or global implications beyond the particular site, such as evaluating processes, mechanisms, or theory under a natural environmental setting.