Investigation of Structural, Optical, Electrical, and Biological Properties of a Porous Platinum Electrode for Neurostimulation Devices.

IF 4.7 Q2 MATERIALS SCIENCE, BIOMATERIALS
ACS Applied Bio Materials Pub Date : 2025-04-21 Epub Date: 2025-04-04 DOI:10.1021/acsabm.4c01974
Lee-Woon Jang, Jeong-Hun Kim, Wonseok Lee, Jung-Hyun Lee, Gwang-Geun Oh, Hachul Jung, Seong-Woo Kim, Dae-Woo Jeon, Tae-Young Ha, Keun-A Chang, Jungsuk Kim
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引用次数: 0

Abstract

The structural and optical properties, as well as the electrical and biological characteristics of a porous platinum (Pt) structure for neurostimulation applications, are investigated. Critical factors such as biocompatibility, electrical performance, and structural and optical differences, which can adversely affect the functionality of implantable devices, are systematically analyzed and compared with general electrodes. By employing an integration of three-dimensional simulations and implantation experiments, we demonstrate that the remarkably extensive surface area, low reflectance, and outstanding peak current values inherent in porous Pt facilitate effective stimulation while simultaneously ensuring a high degree of biological safety. Our findings suggest that these beneficial characteristics collectively position porous Pt as a notably promising candidate for implantable electrodes in biomedical devices.

用于神经刺激装置的多孔铂电极的结构、光学、电学和生物学特性研究。
研究了用于神经刺激的多孔铂(Pt)结构的结构和光学特性,以及电学和生物学特性。系统地分析了生物相容性、电性能、结构和光学差异等可能对可植入装置的功能产生不利影响的关键因素,并与普通电极进行了比较。通过采用三维模拟和植入实验相结合的方法,我们证明了多孔Pt具有非常广泛的表面积、低反射率和突出的峰值电流,有利于有效的刺激,同时确保了高度的生物安全性。我们的研究结果表明,这些有益的特性共同使多孔Pt成为生物医学设备中植入电极的一个非常有前途的候选材料。
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来源期刊
ACS Applied Bio Materials
ACS Applied Bio Materials Chemistry-Chemistry (all)
CiteScore
9.40
自引率
2.10%
发文量
464
期刊介绍: ACS Applied Bio Materials is an interdisciplinary journal publishing original research covering all aspects of biomaterials and biointerfaces including and beyond the traditional biosensing, biomedical and therapeutic applications. The journal is devoted to reports of new and original experimental and theoretical research of an applied nature that integrates knowledge in the areas of materials, engineering, physics, bioscience, and chemistry into important bio applications. The journal is specifically interested in work that addresses the relationship between structure and function and assesses the stability and degradation of materials under relevant environmental and biological conditions.
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