The acute effects of animal and plant-based milk intake before endurance exercise in overweight and obese women: Interplay between lipolysis and proteolysis

Q2 Medicine

Obesity Medicine Pub Date : 2025-03-27 DOI:10.1016/j.obmed.2025.100603

Soheila Moghaddam Eftekhari , Marziyeh Saghebjoo , Fatemeh Islami , Fereshteh Ahmadabadi

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引用次数: 0

Abstract

Aims

Obesity is the underlying cause of several metabolic disorders, and regular endurance exercise (EE) is considered one of the main weight loss strategies. Since females have less muscle mass than males, maintaining muscle mass is crucial for them in specific exercise considerations and nutritional strategies designed to produce weight loss. This study aimed to investigate the response of serum levels of glycerol, urea, insulin-like growth factor-1 (IGF-1), and cortisol to performing an EE session following the consumption of animal and plant-based milk in overweight and obese young women.

Methods

After 8 h of overnight fasting, 10 female participants consumed 500 ml of water, low-fat cow's milk (LFCM), and soy milk (SM), randomly in three sessions, then performed 90-min EE at 65 % VO2max. Biochemical parameters were measured immediately before and after and 1 h after each session of EE.

Results

The glycerol level increased immediately after EE in the LFCM and water groups compared to the baseline (P < 0.001), and decreased 1 h after EE in both consumption groups compared to the immediately after EE (P values 0.002, <0.001; respectively). Despite the significant increase in urea level 1 h after EE compared to the baseline level with SM consumption (P < 0.001) and immediately and 1 h after EE compared to the baseline with LFCM consumption (P values 0.001, <0.001; respectively), the urea levels remained unchanged with water consumption. Cortisol level was decreased immediately and 1 h after EE in all three groups compared to the baseline (P < 0.001).

Conclusions

Drinking LFCM and water before the EE under overnight fasting conditions similarly stimulates lipolysis, as evidenced by comparable increases in glycerol level. Additionally, SM consumption appears to enhance anti-degradation pathways of muscle proteins compared to LFCM, based on lower urea levels post-exercise.

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超重和肥胖妇女耐力运动前动物和植物性牛奶摄入的急性效应：脂肪分解和蛋白质分解之间的相互作用

目的肥胖是几种代谢紊乱的潜在原因，定期耐力运动（EE）被认为是主要的减肥策略之一。由于女性的肌肉量比男性少，因此在特定的运动考虑和旨在减肥的营养策略中，保持肌肉量对她们来说至关重要。本研究旨在探讨超重和肥胖年轻女性在食用动物和植物奶后，血清甘油、尿素、胰岛素样生长因子-1 （IGF-1）和皮质醇水平对情感表达的反应。方法禁食8小时后，10名女性参与者随机分3次饮用500毫升水、低脂牛奶（LFCM）和豆浆（SM），然后以65%最大摄氧量进行90分钟的EE。测定各组EE前后及1 h的生化指标。结果与基线相比，LFCM组和水组在EE后甘油水平立即升高(P <；0.001)，并且在吃完EE后1小时，与吃完EE后立即相比，两组都有所下降(P值0.002,<0.001；分别)。尽管与SM消耗的基线水平相比，EE后1小时尿素水平显著增加(P <；0.001)，与LFCM摄入量的基线相比，EE后立即和1小时(P值0.001,<0.001；尿素水平随水分的消耗而保持不变。与基线相比，三组患者的皮质醇水平立即和1小时后均下降(P <；0.001)。结论：空腹过夜条件下，在EE前饮用LFCM和水同样刺激脂肪分解，甘油水平也相应增加。此外，基于运动后较低的尿素水平，与LFCM相比，SM消耗似乎增强了肌肉蛋白质的抗降解途径。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Obesity Medicine Medicine-Public Health, Environmental and Occupational Health

CiteScore

5.50

自引率

0.00%

发文量

审稿时长

40 days

期刊介绍： The official journal of the Shanghai Diabetes Institute Obesity is a disease of increasing global prevalence with serious effects on both the individual and society. Obesity Medicine focusses on health and disease, relating to the very broad spectrum of research in and impacting on humans. It is an interdisciplinary journal that addresses mechanisms of disease, epidemiology and co-morbidities. Obesity Medicine encompasses medical, societal, socioeconomic as well as preventive aspects of obesity and is aimed at researchers, practitioners and educators alike.