{"title":"The proteins that could be","authors":"Dylan Klein, Vikas Nanda","doi":"10.1038/s41570-025-00710-w","DOIUrl":null,"url":null,"abstract":"In 1998, a protein structure that had not yet been experimentally observed was designed from scratch. 27 years later this work still demonstrates the power of a field that is undergoing an exciting renaissance thanks to advances in machine learning.","PeriodicalId":18849,"journal":{"name":"Nature reviews. Chemistry","volume":"73 1","pages":""},"PeriodicalIF":38.1000,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nature reviews. Chemistry","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1038/s41570-025-00710-w","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
Abstract
In 1998, a protein structure that had not yet been experimentally observed was designed from scratch. 27 years later this work still demonstrates the power of a field that is undergoing an exciting renaissance thanks to advances in machine learning.
期刊介绍:
Nature Reviews Chemistry is an online-only journal that publishes Reviews, Perspectives, and Comments on various disciplines within chemistry. The Reviews aim to offer balanced and objective analyses of selected topics, providing clear descriptions of relevant scientific literature. The content is designed to be accessible to recent graduates in any chemistry-related discipline while also offering insights for principal investigators and industry-based research scientists. Additionally, Reviews should provide the authors' perspectives on future directions and opinions regarding the major challenges faced by researchers in the field.