Dilated cardiomyopathy - guidelines for personalization of care.

IF 1.1 Q4 RESPIRATORY SYSTEM
Antonella Spinelli, Gaetano Marino, Alfredo Macchiusi, Stefania Angela Di Fusco, Carlo Pignalberi, Furio Colivicchi
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Abstract

The term dilated cardiomyopathy (DCM) refers to a family of diseases characterized by complex interactions between environment and genetic predisposition. Diagnostic tools such as cardiac magnetic resonance imaging should be systematically implemented in clinical practice to define the etiological cause and undertake a specific treatment. We present the case of a young man with DCM and severe left ventricular dysfunction. The patient has a family history of sudden cardiac death (SCD). He is affected by a psychiatric pathology and has a history of alcohol and drug addiction. Many diagnostic hypotheses have been considered for etiological research. The use of a wearable defibrillator to temporarily protect the patient from SCD risk pending the completion of the diagnostic path to establish DCM etiology and the implementation of optimal medical therapy was considered. However, because of the underlying psychiatric pathology and the possibility of poor adherence to the maintenance of the wearable device, the patients would not have been sufficiently protected. Due to the young age of the patient, it was decided to make a personalized therapeutic choice, and he underwent implantation of a subcutaneous defibrillator.

扩张型心肌病(DCM)是指以环境和遗传易感性之间复杂的相互作用为特征的疾病家族。在临床实践中,应系统地使用心脏磁共振成像等诊断工具,以明确病因并采取针对性治疗。我们介绍了一例患有 DCM 和严重左心室功能障碍的年轻男性患者。患者有心脏性猝死(SCD)家族史。他患有精神疾病,并有酗酒和吸毒史。在病因学研究中考虑了许多诊断假说。在完成确定 DCM 病因的诊断路径和实施最佳药物治疗之前,曾考虑使用可穿戴除颤器暂时保护患者免受 SCD 风险。然而,由于潜在的精神病理学以及对可穿戴设备维护的依从性可能较差,患者无法得到充分保护。由于患者年龄较小,因此决定对其进行个性化治疗,并为其植入了皮下除颤器。
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来源期刊
CiteScore
3.60
自引率
0.00%
发文量
1
审稿时长
12 weeks
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