{"title":"WRKY75-mediated transcriptional regulation of OASA1 controls leaf senescence in Arabidopsis.","authors":"Qijun Ma, Shuo Xu, Shi Hu, Kaijing Zuo","doi":"10.1111/ppl.70193","DOIUrl":null,"url":null,"abstract":"<p><p>Cysteine plays a crucial role in various processes throughout plant growth and development stages. The gene OASA1 can produce cysteine in Arabidopsis. However, the potential developmental roles of OASA1 have not been explored during senescence. In the present study, the gene OASA1 showed increasing expression during senescence. Compared with Col-0, the mutant oasa1-1 and oasa1-2 showed late leaf senescence, which may be due to disturbed cysteine homeostasis. The mutant exhibited lower total cysteine content and reduced chlorophyll degradation. Meanwhile, WRKY75 promotes cysteine production by inducing the transcription of OASA1 expression, affecting leaf senescence. Our results demonstrate that the senescence-responsive transcription factor WRKY75 directly activates the expression of OASA1 to promote cysteine accumulation and H<sub>2</sub>O<sub>2</sub> content, suggesting a mechanism by which senescence regulates cysteine accumulation in plants.</p>","PeriodicalId":20164,"journal":{"name":"Physiologia plantarum","volume":"177 2","pages":"e70193"},"PeriodicalIF":5.4000,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Physiologia plantarum","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.1111/ppl.70193","RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"PLANT SCIENCES","Score":null,"Total":0}
引用次数: 0
Abstract
Cysteine plays a crucial role in various processes throughout plant growth and development stages. The gene OASA1 can produce cysteine in Arabidopsis. However, the potential developmental roles of OASA1 have not been explored during senescence. In the present study, the gene OASA1 showed increasing expression during senescence. Compared with Col-0, the mutant oasa1-1 and oasa1-2 showed late leaf senescence, which may be due to disturbed cysteine homeostasis. The mutant exhibited lower total cysteine content and reduced chlorophyll degradation. Meanwhile, WRKY75 promotes cysteine production by inducing the transcription of OASA1 expression, affecting leaf senescence. Our results demonstrate that the senescence-responsive transcription factor WRKY75 directly activates the expression of OASA1 to promote cysteine accumulation and H2O2 content, suggesting a mechanism by which senescence regulates cysteine accumulation in plants.
期刊介绍：
Physiologia Plantarum is an international journal committed to publishing the best full-length original research papers that advance our understanding of primary mechanisms of plant development, growth and productivity as well as plant interactions with the biotic and abiotic environment. All organisational levels of experimental plant biology – from molecular and cell biology, biochemistry and biophysics to ecophysiology and global change biology – fall within the scope of the journal. The content is distributed between 5 main subject areas supervised by Subject Editors specialised in the respective domain: (1) biochemistry and metabolism, (2) ecophysiology, stress and adaptation, (3) uptake, transport and assimilation, (4) development, growth and differentiation, (5) photobiology and photosynthesis.
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