Direct navigated focal laser photocoagulation of choroidal neovascularization in central serous chorioretinopathy.

IF 2.1 4区医学 Q3 ENGINEERING, BIOMEDICAL

Lasers in Medical Science Pub Date : 2025-04-03 DOI:10.1007/s10103-025-04425-8

Dmitrii S Maltsev, Alexey N Kulikov, Alexandr S Vasiliev, Alina A Kazak, Yana A Kalinicheva, Jay Chhablani

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引用次数: 0

Abstract

Aim: To report the efficacy and safety of navigated focal laser photocoagulation (FLP) in the management of central serous chorioretinopathy (CSCR) complicated by choroidal neovascularization (CNV).

Materials and methods: This interventional case series included patients with CSCR complicated by CNV, defined as the presence of characteristic OCT angiography features. All patients underwent FLP targeting the area of CNV, using the navigated laser system followed by a minimum six-month follow-up. The main outcome measure was complete resolution of subretinal fluid at the end of follow-up.

Results: This study included 16 eyes of 16 patients (6 males and 10 females, mean age 59.3 ± 7.9 years). Mean baseline CNV area was 0.44 ± 0.23 mm². All eyes achieved complete resolution of SRF at 1.1 ± 0.4 months after FLP. At the beginning and at the end of follow-up best-corrected visual acuity was 0.16 ± 0.17 and 0.07 ± 0.12 LogMAR (p = 0.12), respectively. Central retinal thickness decreased from 372.4 ± 83.06 to 215.3 ± 21.5 μm (p < 0.0001), while subfoveal choroidal thickness remained stable (344.6 ± 101.0 μm at baseline and 316.8 ± 99.9 μm at the end of the follow-up, p = 0.53). No visual or anatomical deterioration was observed during 11.5 ± 7.5 months of follow-up.

Conclusion: Navigated FLP of the area of CNV is an effective and safe option in the management of CSCR complicated by relatively small extrafoveal neovascular membranes.

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中枢性浆液性脉络膜视网膜病变脉络膜新生血管的直接导航激光光凝治疗。

目的：报道导航聚焦激光光凝（FLP）治疗中心性浆液性脉络膜视网膜病变（CSCR）合并脉络膜新生血管（CNV）的疗效和安全性。材料和方法：本介入病例系列包括CSCR合并CNV的患者，定义为存在特征性OCT血管造影特征。所有患者使用导航激光系统对CNV区域进行FLP治疗，随访至少6个月。主要观察指标为随访结束时视网膜下积液的完全溶解。结果：16例患者共16眼，男6例，女10例，平均年龄59.3±7.9岁。平均基线CNV面积为0.44±0.23 mm2。所有眼在FLP后1.1±0.4个月达到SRF完全分辨率。随访开始和结束时最佳矫正视力LogMAR分别为0.16±0.17和0.07±0.12 （p = 0.12）。视网膜中央厚度由372.4±83.06 μm降至215.3±21.5 μm (p)。结论：CNV区导航FLP治疗CSCR合并较小的中央凹外新生血管膜是一种安全有效的选择。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Lasers in Medical Science 医学-工程：生物医学

CiteScore

4.50

自引率

4.80%

发文量

192

审稿时长

3-8 weeks

期刊介绍： Lasers in Medical Science (LIMS) has established itself as the leading international journal in the rapidly expanding field of medical and dental applications of lasers and light. It provides a forum for the publication of papers on the technical, experimental, and clinical aspects of the use of medical lasers, including lasers in surgery, endoscopy, angioplasty, hyperthermia of tumors, and photodynamic therapy. In addition to medical laser applications, LIMS presents high-quality manuscripts on a wide range of dental topics, including aesthetic dentistry, endodontics, orthodontics, and prosthodontics. The journal publishes articles on the medical and dental applications of novel laser technologies, light delivery systems, sensors to monitor laser effects, basic laser-tissue interactions, and the modeling of laser-tissue interactions. Beyond laser applications, LIMS features articles relating to the use of non-laser light-tissue interactions.