Hydrogen Sulfide-Activatable Fluorescence Turn-On Triphenylamine Derivative and Its Application in Real Samples.

IF 2.6 4区 化学 Q2 BIOCHEMICAL RESEARCH METHODS
Lan Yang, Fei Yang, Bo Xu, Zhigang Zhao, Zhichuan Shi
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引用次数: 0

Abstract

A practical and highly selective reactive probe for hydrogen sulfide (H2S), designated as 4-(7-(4-((7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)oxy)phenyl)benzo[c][1,2,5]thiadiazol-4-yl)-N,N-diphenylaniline (BTD), was synthesized through the covalent attachment of the 4-chloro-7-nitro-1,2,3-benzoxadiazole (NBD-Cl) unit to 4-(7-(4-(diphenylamino)phenyl)benzo[c][1,2,5]thiadiazol-4-yl)phenol (BP-OH). The structure of probe BTD was characterized using IR, NMR, and HRMS. Experimental results demonstrate that the fluorescence of BTD significantly increases upon the introduction of H2S, resulting in a distinct color change from colorless to bright orange-red. The detection capability of BTD for H2S was assessed using UV-visible absorption and fluorescence emission spectroscopy. The probe shows significant fluorescence enhancement and can detect H2S quantitatively over a concentration range of 0 to 14 μM, with a low detection limit of 44.85 nM. Furthermore, BTD exhibits excellent recovery rates and accuracy, indicating its practicality for H2S analysis in real samples.

硫化氢可激活荧光开启三苯胺衍生物及其在真实样品中的应用。
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来源期刊
Journal of Fluorescence
Journal of Fluorescence 化学-分析化学
CiteScore
4.60
自引率
7.40%
发文量
203
审稿时长
5.4 months
期刊介绍: Journal of Fluorescence is an international forum for the publication of peer-reviewed original articles that advance the practice of this established spectroscopic technique. Topics covered include advances in theory/and or data analysis, studies of the photophysics of aromatic molecules, solvent, and environmental effects, development of stationary or time-resolved measurements, advances in fluorescence microscopy, imaging, photobleaching/recovery measurements, and/or phosphorescence for studies of cell biology, chemical biology and the advanced uses of fluorescence in flow cytometry/analysis, immunology, high throughput screening/drug discovery, DNA sequencing/arrays, genomics and proteomics. Typical applications might include studies of macromolecular dynamics and conformation, intracellular chemistry, and gene expression. The journal also publishes papers that describe the synthesis and characterization of new fluorophores, particularly those displaying unique sensitivities and/or optical properties. In addition to original articles, the Journal also publishes reviews, rapid communications, short communications, letters to the editor, topical news articles, and technical and design notes.
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