Variants of rhinitis medicamentosa treatment: a systematic review.

IF 1.9 3区 医学 Q2 OTORHINOLARYNGOLOGY
Xi Yang, Kseniya Eremeeva, Valeriy Svistushkin, Daria Lisenkova, Elena Smolyarchuk, Andrey Nedorubov
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引用次数: 0

Abstract

Purpose: Nasal breathing dysfunction resulting from uncontrolled decongestant use is an extremely urgent public health problem. This condition is referred to as rhinitis medicamentosa. Despite the high incidence of patients with this diagnosis, there is still no consensus on treatment tactics. The purpose of this study was to review the available literature on rhinitis medicamentosa treatment and summarize the findings reported in different approaches.

Methods and materials: We conducted a systematic review of PubMed (MEDLINE), The Cochrane Library, and Clinicaltrials.gov databases to identify studies that describe conservative and surgical treatments for rhinitis medicamentosa.

Results: Twelve studies, including 373 patients, met the search criteria. Out of these, seven studies used topical intranasal steroids like budesonide or fluticasone propionate sprays as a conservative treatment. One study used dexamethasone nasal drops. Five studies involved surgical treatment for patients; three of these studies used radiofrequency ablation to reduce the inferior turbinates, while the other two studies used diode laser and kinetic stimulation, respectively.

Conclusion: All studies included in this systematic review demonstrate the high efficacy of the separately presented treatment methods. However, the different design and evaluation methods do not allow us to systematize the data and develop a unified algorithm for treating rhinitis medicamentosa. We see the potential for conducting comparative evidence-based studies on a larger sample, along with the evaluation of long-term treatment results.

变异型鼻炎药物治疗:系统综述。
目的:无节制使用减充血剂导致的鼻呼吸功能障碍是一个极为紧迫的公共卫生问题。这种情况被称为药物性鼻炎。尽管这种病症的发病率很高,但在治疗策略上仍未达成共识。本研究的目的是回顾有关药物性鼻炎治疗的现有文献,并总结不同方法的研究结果:我们对 PubMed (MEDLINE)、The Cochrane Library 和 Clinicaltrials.gov 数据库进行了系统性回顾,以确定描述药物性鼻炎保守疗法和手术疗法的研究:有 12 项研究(包括 373 名患者)符合搜索标准。其中,7 项研究使用布地奈德或丙酸氟替卡松喷雾剂等局部鼻内类固醇作为保守疗法。一项研究使用地塞米松滴鼻剂。五项研究涉及对患者进行手术治疗;其中三项研究使用射频消融术缩小下鼻甲,另外两项研究分别使用二极管激光和动能刺激:结论:本系统性综述中包含的所有研究都证明了分别介绍的治疗方法具有很高的疗效。然而,由于设计和评估方法的不同,我们无法对数据进行系统化处理,也无法制定出治疗药物性鼻炎的统一算法。我们认为有可能对更大样本进行循证比较研究,并对长期治疗效果进行评估。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
5.30
自引率
7.70%
发文量
537
审稿时长
2-4 weeks
期刊介绍: Official Journal of European Union of Medical Specialists – ORL Section and Board Official Journal of Confederation of European Oto-Rhino-Laryngology Head and Neck Surgery "European Archives of Oto-Rhino-Laryngology" publishes original clinical reports and clinically relevant experimental studies, as well as short communications presenting new results of special interest. With peer review by a respected international editorial board and prompt English-language publication, the journal provides rapid dissemination of information by authors from around the world. This particular feature makes it the journal of choice for readers who want to be informed about the continuing state of the art concerning basic sciences and the diagnosis and management of diseases of the head and neck on an international level. European Archives of Oto-Rhino-Laryngology was founded in 1864 as "Archiv für Ohrenheilkunde" by A. von Tröltsch, A. Politzer and H. Schwartze.
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