Biomechanical Properties Measured with Dynamic Scheimpflug Analyzer in Myopic Maculopathy.

IF 4.1 1区医学 Q1 OPHTHALMOLOGY

American Journal of Ophthalmology Pub Date : 2025-03-31 DOI:10.1016/j.ajo.2025.03.046

Kazuki Yashiro, Shuichiro Aoki, Kohdai Kitamoto, Takahiro Arai, Keiko Azuma, Tatsuya Inoue, Ryo Asaoka, Ryo Obata

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引用次数: 0

Abstract

Purpose: Corneal biomechanical properties are associated with axial elongation. We aimed to characterize corneal biomechanical properties in highly myopic eyes with myopic maculopathy (MM).

Design: Retrospective cross-sectional study.

Methods: We included patients examined between June 2022 and August 2023, who underwent corneal visualization Scheimpflug technology (Corvis ST) measurements. MM in highly myopic eyes (axial length >26.0 mm) was evaluated using META-PM classification based on fundus photographs with subfoveal choroidal thickness measured via spectral domain OCT. A linear mixed model was used to analyze the association of MM features with axial length (AL) and corneal biomechanical parameters, followed by model selection using the second order-corrected Akaike Information Criterion.

Results: We included 189 eyes from 109 participants. A significant correlation was observed between AL and biomechanical parameters that characterize maximal corneal deformation (deflection amplitude max and peak distance) and stiffness parameter (stress-strain index) (P < 0.05). Model selection revealed that both AL and deflection amplitude max were independently associated with MM with category ≥2 severe, as well as with subfoveal choroidal thickness in highly myopic eyes (AL > 26.0 mm).

Conclusion: In highly myopic eyes, a greater deflection amplitude max was identified as a risk factor for MM. Corneal biomechanical properties may serve as biomarkers for predicting the development and progression of MM.

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来源期刊

American Journal of Ophthalmology 医学-眼科学

CiteScore

9.20

自引率

7.10%

发文量

406

审稿时长

36 days

期刊介绍： The American Journal of Ophthalmology is a peer-reviewed, scientific publication that welcomes the submission of original, previously unpublished manuscripts directed to ophthalmologists and visual science specialists describing clinical investigations, clinical observations, and clinically relevant laboratory investigations. Published monthly since 1884, the full text of the American Journal of Ophthalmology and supplementary material are also presented online at www.AJO.com and on ScienceDirect. The American Journal of Ophthalmology publishes Full-Length Articles, Perspectives, Editorials, Correspondences, Books Reports and Announcements. Brief Reports and Case Reports are no longer published. We recommend submitting Brief Reports and Case Reports to our companion publication, the American Journal of Ophthalmology Case Reports. Manuscripts are accepted with the understanding that they have not been and will not be published elsewhere substantially in any format, and that there are no ethical problems with the content or data collection. Authors may be requested to produce the data upon which the manuscript is based and to answer expeditiously any questions about the manuscript or its authors.