Brugada pattern changes during tilt table test with high precordial leads. An exploratory data to better understand the dynamic profile

IF 2.2 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL
Eduardo Nolla Silva Pereira, Luciana Sacilotto, Tan Chen Wu, Gabriele D'Arezzo Pessente, Denise Tessariol Hachul, Mauricio Ibrahim Scanavacca, Francisco Carlos da Costa Darrieux
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Abstract

Introduction

Brugada Syndrome (BrS) typically manifests with a dynamic type 1 Brugada pattern (Br1ECGp) that depends on the dominance of the sympathetic or parasympathetic nervous system. This pattern is more prominent during activities that stimulate the vagus nerve, such as sleeping and after meals. By conducting the tilt table test and adding high precordial leads to the standard protocol, it is possible to provoke sympathetic or parasympathetic responses, providing valuable information.

Materials and methods

This was an observational, cross-sectional and hypothesis-generating pilot study. The tilt table test was performed with high precordial leads on three Brugada patients to assess the Br1ECGp during the test. The ECG features were continuously recorded to analyze variations during all phases of the test.

Results

The first patient exhibited a significant Br1ECGp that disappeared during the upward phase of the tilt table test and reappeared during the recovery phase. The second patient had a Br1ECGp in three leads that persisted during both the upward and recovery phases of the tilt table test. The third patient displayed a Br1ECGp in three leads, which was maintained during the upward phase in two leads and recovered during the recovery phase. The third patient was the only one to experience cardioinhibitory syncope.

Conclusion

This study provided insights into the dynamics of the Br1ECGp during the tilt table test when enhanced by high precordial leads. It reaffirmed that the Brugada ECG pattern is influenced by sympathetic or parasympathetic dominance.
高心前导联倾斜试验时Brugada模式的改变。一个探索性的数据,以更好地了解动态剖面
Brugada综合征(BrS)典型表现为动态1型Brugada模式(Br1ECGp),依赖于交感或副交感神经系统的主导地位。这种模式在刺激迷走神经的活动中更为突出,比如睡觉和饭后。通过进行倾斜台测试并在标准方案中加入高心前导联,可以激发交感或副交感神经反应,提供有价值的信息。材料和方法这是一项观察性、横断面性和产生假设的初步研究。对3例Brugada患者进行高心前导联倾斜试验,以评估试验期间的Br1ECGp。连续记录心电图特征,分析试验各阶段的变化。结果1例患者的Br1ECGp在倾斜台试验上升阶段消失,在恢复阶段重新出现。第二例患者的Br1ECGp在倾斜台试验的上升和恢复阶段的三个导联中持续存在。第三例患者在三个导联中显示Br1ECGp,在两个导联中维持上升阶段,并在恢复阶段恢复。第三名患者是唯一出现心抑制性晕厥的患者。结论:本研究揭示了当高心前导联增强时,倾斜台试验期间Br1ECGp的动态变化。再次确认Brugada心电图模式受交感或副交感主导的影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Clinics
Clinics 医学-医学:内科
CiteScore
4.10
自引率
3.70%
发文量
129
审稿时长
52 days
期刊介绍: CLINICS is an electronic journal that publishes peer-reviewed articles in continuous flow, of interest to clinicians and researchers in the medical sciences. CLINICS complies with the policies of funding agencies which request or require deposition of the published articles that they fund into publicly available databases. CLINICS supports the position of the International Committee of Medical Journal Editors (ICMJE) on trial registration.
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