Effects of self-management education on quality of life in patients with epilepsy: A systematic review and meta-analysis

IF 2.3 3区医学 Q2 BEHAVIORAL SCIENCES

Epilepsy & Behavior Pub Date : 2025-04-04 DOI:10.1016/j.yebeh.2025.110393

Yanfang Huang , Min Zhang , Tengteng Liu

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引用次数: 0

Abstract

Background

Self-management education, as a non-pharmacological intervention, aims to help epilepsy patients better control their condition and improve their quality of life. While some studies have shown that self-management education is beneficial for epilepsy patients, its specific effects still require systematic evaluation.

Objective

This study aims to comprehensively assess the impact of self-management education on the quality of life and recurrence frequency of epilepsy patients through a systematic review and meta-analysis.

Methods

This study systematically reviewed literature on self-management education for epilepsy patients from 2014 to 2024. Computer searches were conducted in PubMed, Wiley Library, EMBASE, Web of Science, Cochrane Central, and CNKI databases, covering the period from January 1, 2014, to August 31, 2024, to identify relevant randomized controlled trials (RCTs). Two independent reviewers screened the literature, extracted data, and assessed the risk of bias according to predefined criteria. The primary outcome measures included scores from the Hospital Anxiety and Depression Scale (HADS) for anxiety and depression, the Epilepsy Self-Efficacy Scale (ESES), the Quality of Life in Epilepsy Inventory (QOLIE-31), the Medication Event Monitoring System (MEMS), the Patient Health Questionnaire (PHQ-9), and the Epilepsy Knowledge Questionnaire (EKP).

Results

A total of 9 RCTs involving 1094 patients were included after searching six databases. The results showed that self-management education significantly improved the quality of life of epilepsy patients (SMD = 0.56, 95 % CI [-0.05; 0.18]) and significantly reduced anxiety (SMD = −0.41, 95 % CI [-0.58; −0.23]) and depression symptoms (SMD = −0.40, 95 % CI [-0.76; −0.05]). Additionally, self-management education significantly enhanced patients’ self-efficacy in managing seizures (SMD = 0.32, 95 % CI [0.12; 0.52]).

Conclusion

Self-management education can effectively improve the quality of life and mental health of epilepsy patients, enhancing their ability to cope with the disease, and provides strong evidence for clinical practice. However, due to the high heterogeneity among studies, more high-quality RCTs are needed to further validate these findings.

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来源期刊

Epilepsy & Behavior 医学-行为科学

CiteScore

5.40

自引率

15.40%

发文量

385

审稿时长

43 days

期刊介绍： Epilepsy & Behavior is the fastest-growing international journal uniquely devoted to the rapid dissemination of the most current information available on the behavioral aspects of seizures and epilepsy. Epilepsy & Behavior presents original peer-reviewed articles based on laboratory and clinical research. Topics are drawn from a variety of fields, including clinical neurology, neurosurgery, neuropsychiatry, neuropsychology, neurophysiology, neuropharmacology, and neuroimaging. From September 2012 Epilepsy & Behavior stopped accepting Case Reports for publication in the journal. From this date authors who submit to Epilepsy & Behavior will be offered a transfer or asked to resubmit their Case Reports to its new sister journal, Epilepsy & Behavior Case Reports.