Outcome measures reported by cancer patients treated with tyrosine kinase inhibitors: a methodological study.

IF 1.2 Q3 NURSING
Revista Brasileira De Enfermagem Pub Date : 2025-03-31 eCollection Date: 2025-01-01 DOI:10.1590/0034-7167-2024-0018
Ana Maria Teixeira Pires, Julie Ann Ponto, Eliana Cavalari Teraoka, Fabio Rodrigues Kerbauy, Edvane Birelo Lopes De Domenico
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引用次数: 0

Abstract

Objectives: to validate the content of an outcome measurement instrument with expert judges and to assess the understandability and suitability of this validated instrument with cancer patients undergoing tyrosine kinase inhibitor (TKI) therapy.

Methods: a methodological study, which included the development of an instrument through integrative review, content validity, using the Delphi technique with expert judges, and pilot testing, to verify users' understandability and suitability to the instrument.

Results: literature review allowed constructing PRO-CTCAE® Estudo PROM-TKI Brasil, with 16 items, which was later submitted to validity using the Delphi technique. After the second round, the final instrument consisted of 20 items, with a Content Validity Index (CVI) of 0.878. The pilot test showed that the instrument is understandable and suitable for the target population (CVI of 1.0).

Conclusions: PRO-CTCAE® Estudo PROM-TKI Brasil obtained evidence of validity for use during TKI therapy.

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来源期刊
CiteScore
2.30
自引率
7.70%
发文量
477
审稿时长
21 weeks
期刊介绍: The Revista Brasileira de Enfermagem created in 1932, March 20 is the official publication of the Associação Brasileira de Enfermagem (Brazilian Nursing Association) has as purpose to disseminate the scientific production from different nursing interest areas of knowledge, including those which express the political project of the Association. The Revista Brasileira de Enfermagem is the oldest journal of the Brazilian nursing. Its first title was "Annaes de Enfermagem" from 1932 to 1941, being entitled Anais de Enfermagem" until 1955, when its title was changed to the current.
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