Preoperative predictors of worsened respiratory status after patent ductus arteriosus ligation in preterm infants.

IF 1 4区医学 Q3 PEDIATRICS

Pediatrics International Pub Date : 2025-01-01 DOI:10.1111/ped.70030

Hyo Ju Yang, Seul Gi Park, Soo Yeon Lim, Seh Hyun Kim, Seung Han Shin, Ee-Kyung Kim, Han-Suk Kim

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引用次数: 0

Abstract

Background: Preterm infants with hemodynamically significant patent ductus arteriosus (PDA) may require surgical ligation. Following the surgery, some infants may encounter a deterioration in respiratory status. This study aimed to evaluate the risk factors that can predict worsened respiratory outcomes after PDA surgical ligation.

Methods: A retrospective cohort study was performed on 57 preterm infants born at less than 32 weeks of gestational age and in whom the PDA was surgically ligated between January 2014 and December 2018 at Seoul National University Children's Hospital. Participants were divided into two groups: infants with worsened respiratory outcomes 14 days after ligation and control. Worsened respiratory outcome was defined as an increase in respiratory severity score (RSS) by 30% or more at 14 days after ligation compared to RSS before ligation, or death at 14 days after ligation.

Results: Among the 57 PDA-ligated infants, 12 had worsened respiratory outcomes and 45 did not. The worsened respiratory outcomes were associated with oligohydramnios (adjusted OR 1.38, 95% CI 1.1-1.73, p < 0.01) and lower weight at surgery (adjusted OR 0.99, 95% CI 0.99-0.99, p = 0.02), compared to the control.

Conclusion: Worsened respiratory outcomes after PDA ligation appeared to be associated with oligohydramnios, and lower weight on the day of surgery.

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来源期刊

Pediatrics International 医学-小儿科

CiteScore

2.00

自引率

7.10%

发文量

519

审稿时长

12 months

期刊介绍： Publishing articles of scientific excellence in pediatrics and child health delivery, Pediatrics International aims to encourage those involved in the research, practice and delivery of child health to share their experiences, ideas and achievements. Formerly Acta Paediatrica Japonica, the change in name in 1999 to Pediatrics International, reflects the Journal''s international status both in readership and contributions (approximately 45% of articles published are from non-Japanese authors). The Editors continue their strong commitment to the sharing of scientific information for the benefit of children everywhere. Pediatrics International opens the door to all authors throughout the world. Manuscripts are judged by two experts solely upon the basis of their contribution of original data, original ideas and their presentation.