Olfactory Evoked Potential Produced by Electrical Stimulation for Monitoring Olfactory Function During Endonasal Endoscopic Surgery: A Preliminary Study.

IF 2.3 4区 医学 Q3 CLINICAL NEUROLOGY
Feifan Ouyang, Tianci Feng, Yajing Wang, Weiluo Huang, Laiquan Zou, Yun Ma, Peng Tian, Xiang Liu
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引用次数: 0

Abstract

Purpose: The aim of this study is to develop an intraoperative olfactory monitoring system using olfactory evoked potential produced by electrical stimulation. Furthermore, the study seeks to ascertain the feasibility and safety of olfactory evoked potential. This study lays the groundwork for safeguarding olfactory function during surgical procedures.

Methods: We provided a detailed description of the procedure involving electrical stimulation of the olfactory mucosa to induce olfactory evoked potentials during endonasal endoscopic surgery under general anesthesia. This study enrolled 20 patients undergoing endonasal endoscopic surgery. Before surgery, all patients reported no olfactory complaints, and T&T olfactometry did not detect any olfactory disorders. Olfactory evoked potentials were recorded from various regions of the nasal mucosa and followed by analysis of waveform differentiation, latencies, and amplitudes.

Results: Typical "N1-P1-N2" three-phase waves, consistent with the waveforms of olfactory evoked potentials recorded in previous studies, were collected from the olfactory mucosa in each case. No significant alteration was observed in the patients' olfactory function pre- and postsurgery. The latencies of the "N1-P1-N2" waves recorded during the operation were 12.2 ± 6.9 ms, 28.9 ± 10.0 ms, and 47.1 ± 11.6 ms, respectively, whereas the amplitudes of the "N1-P1" and "P1-N2" waves measured 0.9 and 0.6 μV, respectively.

Conclusions: Intraoperative olfactory monitoring through olfactory evoked potential produced by electrical stimulation is achievable and safe.

鼻内窥镜手术中电刺激产生的嗅觉诱发电位监测嗅觉功能的初步研究。
目的:本研究的目的是开发一种利用电刺激产生的嗅觉诱发电位的术中嗅觉监测系统。此外,本研究试图确定嗅觉诱发电位的可行性和安全性。本研究为外科手术过程中保护嗅觉功能奠定了基础。方法:我们详细描述了在全身麻醉下鼻内窥镜手术中,通过电刺激嗅觉粘膜来诱导嗅觉诱发电位的过程。本研究招募了20例接受鼻内窥镜手术的患者。手术前,所有患者均无嗅觉不适,T&T嗅觉检测未发现任何嗅觉障碍。记录鼻黏膜不同区域的嗅觉诱发电位,并分析波形分化、潜伏期和振幅。结果:每个病例的嗅觉粘膜均采集到典型的“N1-P1-N2”三相波,与以往研究记录的嗅觉诱发电位波形一致。手术前后患者的嗅觉功能未见明显变化。术中“N1-P1- n2”波潜伏期分别为12.2±6.9 ms、28.9±10.0 ms和47.1±11.6 ms,“N1-P1”波和“P1-N2”波振幅分别为0.9和0.6 μV。结论:通过电刺激产生的嗅觉诱发电位进行术中嗅觉监测是安全可行的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of Clinical Neurophysiology
Journal of Clinical Neurophysiology 医学-临床神经学
CiteScore
4.60
自引率
4.20%
发文量
198
审稿时长
6-12 weeks
期刊介绍: ​The Journal of Clinical Neurophysiology features both topical reviews and original research in both central and peripheral neurophysiology, as related to patient evaluation and treatment. Official Journal of the American Clinical Neurophysiology Society.
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