The impact of the menstrual cycle on exacerbations of atopic dermatitis: a systematic review.

IF 3.7 4区医学 Q1 DERMATOLOGY

Clinical and Experimental Dermatology Pub Date : 2025-04-02 DOI:10.1093/ced/llaf153

Niamh Theresa McSwiney, Eliza Hutchison, Rosa Moran, Alexandra Phillips, Daya Sumra, Hannah Wainman

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引用次数: 0

Abstract

Background: Atopic dermatitis (AD) is a chronic pruritic inflammatory skin condition. Patients often report experiencing cutaneous deterioration associated with certain points of their menstrual cycle. Despite this, the literature surrounding this topic remains sparse. This review aims to summarise and compare recent publications surrounding the association between the different stages of the menstrual cycle and exacerbations of atopic dermatitis.

Methods: A literature review was conducted as per PRISMA guidelines using Ovid Medline, Embase, Cochrane Library, PubMed and Web of Science. Search terms and variations on these terms included: menstruation, eczema and atopic dermatitis. A minimum of 2 authors independently screened each abstract and reviewed the full-texts for inclusion.

Results: A total of 16 studies were included. All articles consistently acknowledged premenstrual deterioration in control of atopic dermatitis, typically occurring in the week prior to menstruation.

Conclusion: Our results highlight that the premenstrual exacerbation of AD is a well-recognised phenomenon, typically occurring in the week prior to menstruation. Existing studies are of a low quality and we identified minimal evidence on treatment strategies for premenstrual AD exacerbations. Further large-scale studies are needed to explore treatment options for these patients, such as hormonal therapies.

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月经周期对特应性皮炎加重的影响：一项系统综述。

背景：特应性皮炎（AD）是一种慢性瘙痒性炎症性皮肤疾病。患者经常报告经历皮肤恶化与月经周期的某些点有关。尽管如此，围绕这一主题的文献仍然很少。这篇综述的目的是总结和比较最近发表的关于月经周期不同阶段和特应性皮炎恶化之间关系的文章。方法：根据PRISMA指南，使用Ovid Medline、Embase、Cochrane Library、PubMed和Web of Science进行文献综述。搜索术语和这些术语的变化包括：月经，湿疹和特应性皮炎。至少有2位作者独立筛选每个摘要并审查全文以纳入。结果：共纳入16项研究。所有文章一致承认经前特应性皮炎控制恶化，通常发生在月经前一周。结论：我们的研究结果强调AD经前加重是一个公认的现象，通常发生在月经前一周。现有的研究质量较低，我们发现关于经前阿尔茨海默病加重的治疗策略的证据很少。需要进一步的大规模研究来探索这些患者的治疗选择，例如激素治疗。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical and Experimental Dermatology 医学-皮肤病学

CiteScore

3.20

自引率

2.40%

发文量

389

审稿时长

3-8 weeks

期刊介绍： Clinical and Experimental Dermatology (CED) is a unique provider of relevant and educational material for practising clinicians and dermatological researchers. We support continuing professional development (CPD) of dermatology specialists to advance the understanding, management and treatment of skin disease in order to improve patient outcomes.