Five-year reoperation rates after Schlemm's canal-based glaucoma surgery versus trabeculectomy.

IF 3.3 4区 医学 Q1 OPHTHALMOLOGY
Keyu Hu, Jin Wang, Qing Sang, Dapeng Mou, Ye Zhang, Ningli Wang
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引用次数: 0

Abstract

Objective: To compare 5-year reoperation rates between Schlemm's canal (SC)-based glaucoma surgery and trabeculectomy (Trab), and to identify risk factors for reoperations.

Design: Retrospective case series.

Methods: This retrospective study included patients who underwent glaucoma surgery between January 2017 and December 2021. Propensity score matching was used to identify comparable participants among groups. SC-based glaucoma surgery included gonioscopy-assisted transluminal trabeculotomy, microcatheter-assisted trabeculotomy, ab-interno canaloplasty, canaloplasty, and trabectome. The primary outcome was unanticipated reoperations after the original procedure. Kaplan-Meier survival analysis compared reoperation rates between groups. Univariate and multivariate Cox regression analyses identified risk factors for reoperation.

Results: The final analysis included 112 eyes (106 patients) in the SC-based glaucoma surgery group and 147 eyes (137 patients) in the Trab group. The 5-year cumulative reoperation rate was significantly higher in the Trab group compared to the SC-based glaucoma surgery group (15.4% [93/604] vs 11.9% [72/604], respectively, and p = 0.045). Uncontrolled intraocular pressure (IOP) was the primary indication for reoperations in both groups. Trab surgery, higher preoperative IOP, greater number of preoperative medications, and previous glaucoma surgery history were independent risk factors for reoperation.

Conclusions: SC-based glaucoma surgery showed a significantly lower 5-year reoperation rate than Trab, indicating a more favourable long-term safety profile. Trab surgery, higher preoperative IOP, more preoperative medications, and previous glaucoma surgery history were identified as independent risk factors for reoperation, which may help identify patients at higher risk for reoperation and potentially improve postoperative management.

施莱姆氏青光眼手术与小梁切除术后5年的再手术率。
目的:比较Schlemm’s canal (SC)青光眼手术与小梁切除术(Trab)青光眼5年再手术率,并探讨再手术的危险因素。设计:回顾性病例系列。方法:本回顾性研究纳入了2017年1月至2021年12月期间接受青光眼手术的患者。倾向评分匹配用于识别组间可比较的参与者。以sc为基础的青光眼手术包括镜下辅助腔内小梁切开术、微导管辅助小梁切开术、小梁成形术、小梁成形术和小梁切除术。主要结果是原手术后的意外再手术。Kaplan-Meier生存分析比较各组再手术率。单因素和多因素Cox回归分析确定了再手术的危险因素。结果:sc基青光眼手术组112只眼(106例),Trab组147只眼(137例)。Trab组5年累计再手术率明显高于sc组(15.4% [93/604]vs 11.9% [72/604], p = 0.045)。眼压失控是两组再手术的主要指征。青光眼手术、术前IOP较高、术前用药较多、既往青光眼手术史是再手术的独立危险因素。结论:sc基青光眼手术的5年再手术率明显低于Trab,表明其具有更有利的长期安全性。手术难度大、术前IOP较高、术前用药较多、既往青光眼手术史为再手术的独立危险因素,有助于识别再手术高风险患者,改善术后管理。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
3.20
自引率
4.80%
发文量
223
审稿时长
38 days
期刊介绍: Official journal of the Canadian Ophthalmological Society. The Canadian Journal of Ophthalmology (CJO) is the official journal of the Canadian Ophthalmological Society and is committed to timely publication of original, peer-reviewed ophthalmology and vision science articles.
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