{"title":"PHS1ΔP as a promising tool to study microtubule-related processes in plant sciences.","authors":"D-C Trinh","doi":"10.1111/plb.70019","DOIUrl":null,"url":null,"abstract":"<p><p>Microtubules are an essential cell component that controls various biological processes, notably cell division and cellulose deposition in the cell wall. Traditionally, research involving microtubules relies on analysing mutants with altered microtubule properties or treating plant tissues with drugs that interfere with microtubule behaviours. Both approaches have problems, such as not being specific. Recently, a modified version of the tubulin kinase PROPYZAMID-HYPERSENSITIVE 1 (PHS1), named PHS1ΔP, that can efficiently depolymerize microtubules has emerged as a promising tool to manipulate microtubules with high spatial and temporal accuracy. This has been successfully used to address several microtubule-related research questions and is expected to be adopted more widely by researchers in the future.</p>","PeriodicalId":220,"journal":{"name":"Plant Biology","volume":" ","pages":""},"PeriodicalIF":4.2000,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Plant Biology","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.1111/plb.70019","RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"PLANT SCIENCES","Score":null,"Total":0}
引用次数: 0
Abstract
Microtubules are an essential cell component that controls various biological processes, notably cell division and cellulose deposition in the cell wall. Traditionally, research involving microtubules relies on analysing mutants with altered microtubule properties or treating plant tissues with drugs that interfere with microtubule behaviours. Both approaches have problems, such as not being specific. Recently, a modified version of the tubulin kinase PROPYZAMID-HYPERSENSITIVE 1 (PHS1), named PHS1ΔP, that can efficiently depolymerize microtubules has emerged as a promising tool to manipulate microtubules with high spatial and temporal accuracy. This has been successfully used to address several microtubule-related research questions and is expected to be adopted more widely by researchers in the future.
期刊介绍：
Plant Biology is an international journal of broad scope bringing together the different subdisciplines, such as physiology, molecular biology, cell biology, development, genetics, systematics, ecology, evolution, ecophysiology, plant-microbe interactions, and mycology.
Plant Biology publishes original problem-oriented full-length research papers, short research papers, and review articles. Discussion of hot topics and provocative opinion articles are published under the heading Acute Views. From a multidisciplinary perspective, Plant Biology will provide a platform for publication, information and debate, encompassing all areas which fall within the scope of plant science.
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