Detection of Serratia marcescens and Mierococcus lysodeikticus Bacterial Cells Using Cerium Oxide/Transition Metal Dichalcogenides Heterostructure-Based Surface Plasmon Resonance Sensor

Abstract

This article explores a novel surface plasmon resonance sensor for detecting the Serratia marcescens and Mierococcus lysodeikticus bacteria cells employing the cerium oxide (CeO₂) and transition metal dichalcogenides heterostructure. The proposed sensor is designed based on the Kretschmann configuration, where silver (Ag) is deposited over a prism's surface to excite the surface plasmons. The transfer matrix method and angular interrogation technique are exploited for analyzing the sensor's performance at a wavelength of 633 nm. Firstly, the optimization of the prism and metal film is analyzed by selecting the minimum reflectance, better sensitivity, and quality factor. Secondly, the influence of the proposed structure in the sensor is executed by the performances of different structures, which are made with defined layers. Thirdly, different sensing parameters are analyzed for the considered bacterial cells, resulting in the maximum attained parameters being a sensitivity of 369.40° RIU⁻¹, QF of 151.35 RIU⁻¹, and detection accuracy of 7.57. Finally, the comparative study also shows the noteworthy enhancement using the proposed sensor compared with existing work. Therefore, the proposed sensor can be used as a carrier for detecting the bacterial cells and establishing a new platform for biomolecular and biomedical applications.