Multiple Long-Term Chronic Conditions Are Associated with Long-term Declined Physical Quality of Life in Older Adults with or at Risk of Knee Osteoarthritis 8257

IF 3.6 2区医学 Q1 REHABILITATION

Archives of physical medicine and rehabilitation Pub Date : 2025-04-01 DOI:10.1016/j.apmr.2025.01.041

Aqeel Alenazi, Badr Alqahtani

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引用次数: 0

Abstract

Objectives

To examine the association of baseline multiple long-term chronic conditions (MLTCs) with physical and mental health-related quality of life (HRQOL) over time among older adults with or at risk of knee osteoarthritis.

Design

This study is a prospective longitudinal cohort design over 96 months of follow-up.

Setting

This study used multisite data from the Osteoarthritis Initiatives.

Participants

For the current study, only older adults from the Osteoarthritis Initiative were selected who were 60 years and older at baseline. Based on Charlson comorbidity index, all participants were classified into 3 groups: no chronic condition (n=1828), one chronic condition (n=417), and MLTCs (having ≥2 chronic conditions) (n=315).

Interventions

Not applicable.

Main Outcome Measures

Physical and mental component summaries for HRQOL were assessed over 96 months of follow-up using the 12-item Short Form Health Survey.

Results

A total of 2560 older adults were included with 12.2% prevalence of MLTC. The results showed that participants with 1 chronic disease (beta [B]=−2.42, P<.001) and MLTCs (B=−3.58, P<.001) were associated with significantly declined physical component summary for HRQOL over time after adjustments for age, sex, race, educational level, body mass index, depressive symptoms, physical activity, KL for the right knee, and KL for the left knee. Mental component summary for HRQOL was not significantly associated with MLTC.

Conclusions

Older adults with or at risk of knee osteoarthritis who had baseline one chronic disease and MLTCs had significantly overtime declined physical HRQOL. Future work is needed to investigate the potential treatment strategies to improve physical HRQOL in this population.

Disclosures

none.

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来源期刊

Archives of physical medicine and rehabilitation 医学-康复医学

CiteScore

6.20

自引率

4.70%

发文量

495

审稿时长

38 days

期刊介绍： The Archives of Physical Medicine and Rehabilitation publishes original, peer-reviewed research and clinical reports on important trends and developments in physical medicine and rehabilitation and related fields. This international journal brings researchers and clinicians authoritative information on the therapeutic utilization of physical, behavioral and pharmaceutical agents in providing comprehensive care for individuals with chronic illness and disabilities. Archives began publication in 1920, publishes monthly, and is the official journal of the American Congress of Rehabilitation Medicine. Its papers are cited more often than any other rehabilitation journal.