Overview of ADPKD in Pregnancy

IF 5.7 2区医学 Q1 UROLOGY & NEPHROLOGY

Kidney International Reports Pub Date : 2025-04-01 DOI:10.1016/j.ekir.2024.12.035

Ruth E. Campbell , Charles L. Edelstein , Michel Chonchol

引用次数: 0

Abstract

Autosomal dominant polycystic kidney disease (ADPKD) is a systemic disorder that often affects patients in their third to fifth decades of life and is characterized by kidney cysts, chronic kidney disease (CKD), hypertension, and hepatic cysts. The development of clinical symptoms often coincides with childbearing years. Consequently, there are several considerations regarding pregnant patients with ADPKD. In this review, we detail the effects and management of ADPKD in the peripartum period and discuss family planning options, including assisted reproductive techniques (ART) and preimplantation genetic testing.

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妊娠期ADPKD的概述

常染色体显性多囊肾病（ADPKD）是一种全身性疾病，通常影响患者的第三至第五十年的生活，其特征是肾囊肿，慢性肾病（CKD），高血压和肝囊肿。临床症状的发展往往与生育年龄相吻合。因此，对于患有ADPKD的孕妇，有几点需要考虑。在这篇综述中，我们详细介绍了围产期ADPKD的影响和管理，并讨论了计划生育的选择，包括辅助生殖技术（ART）和植入前基因检测。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Kidney International Reports Medicine-Nephrology

CiteScore

7.70

自引率

3.30%

发文量

1578

审稿时长

8 weeks

期刊介绍： Kidney International Reports, an official journal of the International Society of Nephrology, is a peer-reviewed, open access journal devoted to the publication of leading research and developments related to kidney disease. With the primary aim of contributing to improved care of patients with kidney disease, the journal will publish original clinical and select translational articles and educational content related to the pathogenesis, evaluation and management of acute and chronic kidney disease, end stage renal disease (including transplantation), acid-base, fluid and electrolyte disturbances and hypertension. Of particular interest are submissions related to clinical trials, epidemiology, systematic reviews (including meta-analyses) and outcomes research. The journal will also provide a platform for wider dissemination of national and regional guidelines as well as consensus meeting reports.