Peroral endoscopic myotomy (POEM) as a treatment for pediatric achalasia: Multicenter study and first results

Abstract

Introduction

Laparoscopic Heller miotomy of achalasia has been classically recognized as the gold standard management in children. There is increasing experience with the peroral endoscopic miotomy (POEM) approach in pediatrics, although the series published are scarce. The objective of this study was to present our experience in primary or secondary treatment of pediatric achalasia by POEM and its clinical success rate.

Methods

We performed a retrospective review of pediatric patients with achalasia who underwent POEM in some national centers from October 2016 to January 2023. We evaluated clinical efficacy (Eckardt score ≤3), demographic characteristics, intraoperative, preoperative and postoperative, complications, and follow-up.

Results

Fifteen POEM were performed in fourteen pediatric patients (aged 12–18 years) with achalasia. POEM was the first line treatment in 11 patients, but 4 (21.3%) had previous treatment: 1 (7,1%) pneumatic balloon dilation and 2 (14,2%) laparoscopic Heller myotomy and 1 (7,1%) previous POEM. The average age was 15 years (SD ± 1,9). The baseline Eckardt score was 7,5 (SD: ± 1,8), with the baseline GERD score being 6 (SD: ± 2,9). There was a Clavien-Dindo grade 2 postoperative adverse event corresponding to mild pneumonia (7,1%). The postoperative Eckardt and GERD score after 12 months of follow-up were 0.7 (SD ± 1,2) and 0,5 (SD ± 0,7). The study has a success rate greater than 93%.

Conclusions

POEM seems a safe and effective procedure, with a short postoperative period for treatment of pediatric achalasia.