The multiple mediating effects of social support and depressive symptoms on the relationship between frailty and cognitive function in older patients with heart failure: A cross-sectional study

IF 2.5 3区医学 Q3 GERIATRICS & GERONTOLOGY

Geriatric Nursing Pub Date : 2025-04-03 DOI:10.1016/j.gerinurse.2025.03.015

Jian Liu PhD , Simeng Zhang MSN , Zongke Long MSN , Zhiwei Wang PhD , Jiurui Wang MSN , Xiaorong Luan Ph.D., RN

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引用次数: 0

Abstract

Aims

The aim of this study was to test the multiple mediating effects of social support and depression symptoms on the relationship between frailty and cognitive function in older patients with heart failure.

Methods and results

We used a convenience sampling method to recruit 444 older patients with heart failure who met the inclusion criteria from a university-affiliated general hospital.

Multiple mediation analyses revealed that the relationship between frailty and cognitive function was influenced by social support (effect: -0.383, 95% CI [-0.774, -0.072]) and depressive symptoms (effect: -0.349, 95% CI [-0.710, -0.134]) both individually and in tandem (effect: -0.276, 95% CI [-0.591, - 0.106]).

Conclusion

Social support and depressive symptoms are multiple mediators of the relationship between frailty and cognitive function. Healthcare providers should implement interventions that focus on maximizing social return and minimizing depressive symptoms to mitigate the decline in cognitive function.

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社会支持和抑郁症状在老年心力衰竭患者虚弱与认知功能关系中的多重中介作用：一项横断面研究

目的探讨社会支持和抑郁症状在老年心力衰竭患者虚弱与认知功能关系中的多重中介作用。方法和结果采用方便抽样方法，从某大学附属综合医院招募符合纳入标准的老年心力衰竭患者444例。多重中介分析显示，虚弱和认知功能之间的关系受到社会支持（效应：-0.383,95% CI[-0.774, -0.072]）和抑郁症状（效应：-0.349,95% CI[-0.710, -0.134]）的单独和连带影响（效应：-0.276,95% CI[-0.591, - 0.106]）。结论社会支持和抑郁症状在衰弱与认知功能的关系中起多重中介作用。医疗保健提供者应实施干预措施，重点是最大化社会回报和最小化抑郁症状，以减轻认知功能的下降。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Geriatric Nursing 医学-护理

CiteScore

3.80

自引率

7.40%

发文量

257

审稿时长

>12 weeks

期刊介绍： Geriatric Nursing is a comprehensive source for clinical information and management advice relating to the care of older adults. The journal''s peer-reviewed articles report the latest developments in the management of acute and chronic disorders and provide practical advice on care of older adults across the long term continuum. Geriatric Nursing addresses current issues related to drugs, advance directives, staff development and management, legal issues, client and caregiver education, infection control, and other topics. The journal is written specifically for nurses and nurse practitioners who work with older adults in any care setting.