A chiral electrochemiluminescence sensor based on isoquinoline complex for the detection of cysteine enantiomers

IF 2.7 4区材料科学 Q3 MATERIALS SCIENCE, MULTIDISCIPLINARY

Materials Letters Pub Date : 2025-03-29 DOI:10.1016/j.matlet.2025.138491

Qian Duan, Bo Liu, Min Sui, Maohu Wei, Peng Liu

引用次数: 0

Abstract

This study developed a chiral ECL sensor for detecting cysteine enantiomers using isoquinoline complexes. The sensor was fabricated by immobilizing [Cu(µ-ox)(isq)₂]_n and [Zn₂(bdc)(l-lac)(dmf)] on an electrode. After optimizing fabrication and detection conditions, the sensor achieved high sensitivity, selectivity, and stability in PBS. It showed a linear correlation between ECL signal intensity and cysteine concentration, with good reproducibility and high selectivity for cysteine enantiomers over other amino acids. This robust sensor provides a practical method for analyzing cysteine enantiomers in complex biological samples.

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来源期刊

Materials Letters 工程技术-材料科学：综合

CiteScore

5.60

自引率

3.30%

发文量

1948

审稿时长

50 days

期刊介绍： Materials Letters has an open access mirror journal Materials Letters: X, sharing the same aims and scope, editorial team, submission system and rigorous peer review. Materials Letters is dedicated to publishing novel, cutting edge reports of broad interest to the materials community. The journal provides a forum for materials scientists and engineers, physicists, and chemists to rapidly communicate on the most important topics in the field of materials. Contributions include, but are not limited to, a variety of topics such as: • Materials - Metals and alloys, amorphous solids, ceramics, composites, polymers, semiconductors • Applications - Structural, opto-electronic, magnetic, medical, MEMS, sensors, smart • Characterization - Analytical, microscopy, scanning probes, nanoscopic, optical, electrical, magnetic, acoustic, spectroscopic, diffraction • Novel Materials - Micro and nanostructures (nanowires, nanotubes, nanoparticles), nanocomposites, thin films, superlattices, quantum dots. • Processing - Crystal growth, thin film processing, sol-gel processing, mechanical processing, assembly, nanocrystalline processing. • Properties - Mechanical, magnetic, optical, electrical, ferroelectric, thermal, interfacial, transport, thermodynamic • Synthesis - Quenching, solid state, solidification, solution synthesis, vapor deposition, high pressure, explosive