Distribution patterns and ecological risks of antibiotic resistance genes in the Yap Trench

IF 11.4 1区环境科学与生态学 Q1 ENGINEERING, ENVIRONMENTAL

Water Research Pub Date : 2025-04-01 DOI:10.1016/j.watres.2025.123589

Jianxing Sun , Yuan-Guo Xie , Hongbo Zhou , Lei Chen , Yan-Ni Qu , Haina Cheng , Zhu Chen , Zheng-Shuang Hua , Yuguang Wang

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Abstract

Antibiotic resistance genes (ARGs) are a global environmental concern, yet their vertical distribution in pristine marine ecosystems remains poorly understood. This study investigated the distribution of ARG distribution in both the water column and sediments of the Yap Trench, which reaches depths over 6500 m Results revealed significant variations in ARG diversity and abundance across depths and habitats. The deep-water (DW) zones exhibited the highest diversity (291–472 subtypes) and abundance (1.79 copies/cell), followed by upper-water (UW) zones (240–314 subtypes, 0.31 copies/cell), while sediments had the lowest diversity (72–236 subtypes) and abundance (0.03 copies/cell). The most prevalent resistance genes included those conferring resistance to multidrug, polymyxin, and beta-lactam in the Yap Trench. ARG distribution closely correlated with microbial hosts, including Pseudomonadota, Chloroflexota, Bacteroidota, and Planctomycetota. Risk assessment showed high-risk ARGs were most abundant in DW zones, with pathogenic groups capable of spreading multiple ARGs (e.g., macAB, mexDJKW, mdtE, muxC). This study provides a systematic understanding of the distribution patterns and potential risks of ARGs in the water column and sediments of pristine marine ecosystems, underscoring the penetration of antibiotic pollution into the deep ocean and offering new insights for marine pollution control strategies.

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来源期刊

Water Research 环境科学-工程：环境

CiteScore

20.80

自引率

9.40%

发文量

1307

审稿时长

38 days

期刊介绍： Water Research, along with its open access companion journal Water Research X, serves as a platform for publishing original research papers covering various aspects of the science and technology related to the anthropogenic water cycle, water quality, and its management worldwide. The audience targeted by the journal comprises biologists, chemical engineers, chemists, civil engineers, environmental engineers, limnologists, and microbiologists. The scope of the journal include: •Treatment processes for water and wastewaters (municipal, agricultural, industrial, and on-site treatment), including resource recovery and residuals management; •Urban hydrology including sewer systems, stormwater management, and green infrastructure; •Drinking water treatment and distribution; •Potable and non-potable water reuse; •Sanitation, public health, and risk assessment; •Anaerobic digestion, solid and hazardous waste management, including source characterization and the effects and control of leachates and gaseous emissions; •Contaminants (chemical, microbial, anthropogenic particles such as nanoparticles or microplastics) and related water quality sensing, monitoring, fate, and assessment; •Anthropogenic impacts on inland, tidal, coastal and urban waters, focusing on surface and ground waters, and point and non-point sources of pollution; •Environmental restoration, linked to surface water, groundwater and groundwater remediation; •Analysis of the interfaces between sediments and water, and between water and atmosphere, focusing specifically on anthropogenic impacts; •Mathematical modelling, systems analysis, machine learning, and beneficial use of big data related to the anthropogenic water cycle; •Socio-economic, policy, and regulations studies.